Plasma Aldosterone Concentration and Plasma Renin Activity Decrease during the Third Trimester in Women with Twin Pregnancies

Koyama, Takahiro; Yamada, Takashi; Furuta, Itsuko; Morikawa, Mamoru; Yamada, Takahiro; Minakami, Hisanori

Plasma Aldosterone Concentration and Plasma Renin Activity Decrease during the Third Trimester in Women with Twin Pregnancies

Koyama, Takahiro; Yamada, Takashi; Furuta, Itsuko et al.

Hypertension in Pregnancy, 2012, 31(4), 419-426

Permalink : https://hdl.handle.net/2115/53469

このアイテムのアクセス数:918件（2026-10-12 19:39 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
Hypertens Preqnancy_31(4)_419-426	pdf	1.17 MB	1,449

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/53469
タイトル	Plasma Aldosterone Concentration and Plasma Renin Activity Decrease during the Third Trimester in Women with Twin Pregnancies
著者	Koyama, Takahiro ; Yamada, Takashi ; Furuta, Itsuko ; Morikawa, Mamoru ; Yamada, Takahiro ; Minakami, Hisanori
著者名 Koyama, Takahiro
e-Rad_Researcher 20374283 著者名 Yamada, Takashi
e-Rad_Researcher 70238682 著者名 Furuta, Itsuko
e-Rad_Researcher 00374380 著者名 Morikawa, Mamoru
e-Rad_Researcher 20419948 著者名 Yamada, Takahiro
e-Rad_Researcher 40102256 著者名 Minakami, Hisanori
言語	英語
キーワード	aldosterone
	hypertension
	preeclampsia
	renin activity
	twin pregnancy
発行日	2012-11
出版者	Informa Healthcare
収録物名	Hypertension in Pregnancy
巻(号)	31(4)
ページ	419-426
抄録	Objective: Changes in the plasma aldosterone concentration (PAC) and the plasma renin activity (PRA) have not been extensively studied in women with twin pregnancies. Methods: The PAC and PRA levels were determined during the second and third trime-sters and on postpartum day 3 in 14 normotensive women with twin pregnancies and 80 normotensive and 7 preeclamptic women with singleton pregnancies. Results: In women with twin pregnancies, elevated PAC and PRA levels (598 ± 248 pg/mL and 10.0 ±4.7 ng/ mL/h, respectively) in the second trimester decreased significantly during the third trimester (to 396 ± 210 pg/mL and 3.5 ± 2.9 ng/mL/h, respectively), whereas the corre-sponding PAC increased significantly (from 421 ± 207 to 667 ± 371 pg/mL) and the PRA did not change significantly (from 7.3 ± 3.4 to 6.9 ± 4.2 ng/mL/h) in women with normal singleton pregnancies. These changes in the PAC and PRA levels in women with twin pregnancies resembled those in hypertensive women with singleton pregnancies. Conclusions: In women with twin pregnancies, both the PAC and PRA levels were significantly enhanced during the second trimester, whereas those in the third trimester were significantly reduced compared with those in women with normal singleton pregnancies.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	1064-1955
EISSN	1525-6065
NCID	AA10910120
関連情報	PMID 22676457
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.3109/10641955.2012.690057