First-trimester serum folate levels and subsequent risk of abortion and preterm birth among Japanese women with singleton pregnancies

Yamada, Takashi; Morikawa, Mamoru; Yamada, Takahiro; Kishi, Reiko; Sengoku, Kazuo; Endo, Toshiaki; Saito, Tsuyoshi; Cho, Kazutoshi; Minakami, Hisanori

First-trimester serum folate levels and subsequent risk of abortion and preterm birth among Japanese women with singleton pregnancies

Yamada, Takashi; Morikawa, Mamoru; Yamada, Takahiro et al.

Archives of Gynecology and Obstetrics, 2013, 287(1), 9-14

Permalink : https://hdl.handle.net/2115/54109

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アクセス権	open access
URI	https://hdl.handle.net/2115/54109
タイトル	First-trimester serum folate levels and subsequent risk of abortion and preterm birth among Japanese women with singleton pregnancies
著者	Yamada, Takashi ; Morikawa, Mamoru ; Yamada, Takahiro ; Kishi, Reiko ; Sengoku, Kazuo ; Endo, Toshiaki ; Saito, Tsuyoshi ; Cho, Kazutoshi ; Minakami, Hisanori
e-Rad_Researcher 20374283 著者名 Yamada, Takashi
e-Rad_Researcher 00374380 著者名 Morikawa, Mamoru
e-Rad_Researcher 20419948 著者名 Yamada, Takahiro
e-Rad_Researcher 80112449 著者名 Kishi, Reiko
著者名 Sengoku, Kazuo
著者名 Endo, Toshiaki
著者名 Saito, Tsuyoshi
e-Rad_Researcher 10312365 著者名 Cho, Kazutoshi
e-Rad_Researcher 40102256 著者名 Minakami, Hisanori
言語	英語
キーワード	Abortion
	Nutrition
	Preterm birth
	Serum folate
発行日	2013-01
出版者	Springer-Verlag
収録物名	Archives of Gynecology and Obstetrics
巻(号)	287(1)
ページ	9-14
抄録	Objectives: To determine whether a low serum folate level during the first trimester predicts subsequent late abortion, preterm birth, or fetal growth restriction (FGR). Study design: A prospective cohort study involving 5,075 women whose serum folate levels were measured during the first trimester. The participants were informed of their serum folate levels. Results: The pregnancy duration, birthweight, rate of late abortion/preterm birth, and the rate of FGR did not differ significantly among four groups classified according to folate status. The mean serum folate levels did not differ among quartiles classified according to the gestational week at the time of delivery. Nineteen of the 20 women with folate deficiency gave birth at term to infants with a birthweight of 3,132 ± A 321 g; only one infant had FGR. Conclusion: Low serum folate levels during the first trimester were not associated with the risk of late abortion, preterm birth, or FGR.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	© 2012 Springer. The final publication is available at www.springerlink.com
PISSN	0932-0067
関連情報	PMID 22875049
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s00404-012-2501-5