Evaluation of inter-observer variability of bladder boundary delineation on cone-beam CT

Nishioka, Kentaro; Shimizu, Shinichi; Kinoshita, Rumiko; Inoue, Tetsuya; Onodera, Shunsuke; Yasuda, Koichi; Harada, Keiichi; Nishikawa, Yukiko; Onimaru, Rikiya; Shirato, Hiroki

Evaluation of inter-observer variability of bladder boundary delineation on cone-beam CT

Nishioka, Kentaro; Shimizu, Shinichi; Kinoshita, Rumiko et al.

Radiation Oncology, 2013, 8(1), 185

Permalink : https://hdl.handle.net/2115/54719

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アクセス権	open access
URI	https://hdl.handle.net/2115/54719
タイトル	Evaluation of inter-observer variability of bladder boundary delineation on cone-beam CT
著者	Nishioka, Kentaro ; Shimizu, Shinichi ; Kinoshita, Rumiko ; Inoue, Tetsuya ; Onodera, Shunsuke ; Yasuda, Koichi ; Harada, Keiichi ; Nishikawa, Yukiko ; Onimaru, Rikiya ; Shirato, Hiroki
e-Rad_Researcher 80463743 著者名 Nishioka, Kentaro
e-Rad_Researcher 50463724 著者名 Shimizu, Shinichi
e-Rad_Researcher 70507582 著者名 Kinoshita, Rumiko
e-Rad_Researcher 10431363 著者名 Inoue, Tetsuya
著者名 Onodera, Shunsuke
e-Rad_Researcher 00431362 著者名 Yasuda, Koichi
著者名 Harada, Keiichi
著者名 Nishikawa, Yukiko
e-Rad_Researcher 80374461 著者名 Onimaru, Rikiya
e-Rad_Researcher 20187537 著者名 Shirato, Hiroki
言語	英語
キーワード	Bladder cancer
	Image guided radiotherapy
	Cone beam CT
	Inter-observer variability
発行日	2013-07-23
出版者	BioMed Central Ltd
収録物名	Radiation Oncology
巻(号)	8(1)
ページ	185
抄録	Background: In-room cone-beam computerized tomography (CBCT) imaging is a promising method to reduce setup errors, especially in organs such as the bladder that often have large intrafractional variations due to organ movement. CBCT image quality is limited by low contrast and imaging artifacts, but few data have been reported about inter-observer variability of bladder boundary delineation on CBCT. The aim of this work was to analyze and evaluate the inter-observer contouring uncertainties of bladder boundary delineation on CBCT images in a prospective fashion. Methods: Five radiation oncologists contoured 10 bladders using the CBCT datasets of consecutive 10 patients (including 4 females) who were irradiated to the pelvic region. Prostates were also contoured in male patients. Patients who had had prostatectomy were excluded. The coefficient of variation (COV), conformity index (CIgen), and coordinates of center-of-mass (COM) of the bladder and prostate were calculated for each patient. Results: The mean COV for the bladder and prostate was 0.08 and 0.20, respectively. The mean CIgen of the bladder and prostate was 0.81 and 0.66, respectively. The root mean square (RMS) of the inter-observer standard deviation (σ) of the COM displacement in the left-right (LR) and anterior-posterior (AP) direction was 0.79, 0.87 and 0.54 for the bladder and 0.63, 0.99 and 1.72 for the prostate. Regarding the mean COV and CIgen for the bladder, the differences between males and females were not significant. Conclusions: Inter-observer variability for bladder delineation on CBCT images was substantially small regardless of gender. We believe that our results support the applicability of CBCT in adaptive radiotherapy for bladder cancer.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 3.0 Unported
PISSN	1748-717X
関連情報	PMID 23879876
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1186/1748-717X-8-185