open access

https://hdl.handle.net/2115/55678

The effects of collagen hydrogel implantation in buccal dehiscence defects in beagles.

英語

scafforld barrier

2007-12-30

日本再生歯科医学会

Journal of oral tissue engineering

5(2)

87-95

Type I collagen hydrogel treated by an ascorbate-copper ion crosslinking system is highly biocompatible and highly degradable in the body. The purpose of this study was to examine the effect of collagen hydrogel on periodontal wound healing in beagles. Sixty-four periodontal dehiscence type defects were created on the buccal roots of four beagles. Subsequently, collagen hydrogel was implanted in each defect in the experimental group and sutured, and, in the control group, the defect was sutured without any application of collagen hydrogel. The percentage of the length of new bone and new cementum in the experimental group was significantly greater than that in the control group at weeks 4 (p<0.01) and 8 (p<0.05). Significantly more junctional epithelium was observed in the control group than in the experimental group at weeks 2 (p<0.01) and 4 (p<0.05). These findings thus indicate that periodontal regeneration was stimulated by collagen hydrogel implantation in beagles.

学術雑誌論文

Version of Record

日本再生歯科医学会(利用は著作権の範囲内に限られます)

1348-9623

AA1195240X