Outcome of Metastasectomy for Urothelial Carcinoma: A Multi-Institutional Retrospective Study in Japan

Abe, Takashige; Kitamura, Hiroshi; Obara, Wataru et al.

Journal of Urology, 2014, 191(4), 932-936

Permalink : https://hdl.handle.net/2115/56347

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アクセス権
open access
URI
https://hdl.handle.net/2115/56347
タイトル
Outcome of Metastasectomy for Urothelial Carcinoma: A Multi-Institutional Retrospective Study in Japan
著者
Abe, Takashige ; Kitamura, Hiroshi ; Obara, Wataru ; Matsumura, Nagahide ; Tsukamoto, Taiji ; Fujioka, Tomoaki ; Hara, Isao ; Murai, Sachiyo ; Shinohara, Nobuo ; Nonomura, Katsuya
e-Rad_Researcher
10399842
著者名
Abe, Takashige
著者名
Kitamura, Hiroshi
著者名
Obara, Wataru
著者名
Matsumura, Nagahide
著者名
Tsukamoto, Taiji
著者名
Fujioka, Tomoaki
著者名
Hara, Isao
著者名
Murai, Sachiyo
e-Rad_Researcher
90250422
著者名
Shinohara, Nobuo
e-Rad_Researcher
60113750
著者名
Nonomura, Katsuya
言語
英語
キーワード
urinary bladder
urothelium
carcinoma
lymph nodes
neoplasm metastasis
発行日
2014-04
出版者
Elsevier
収録物名
Journal of Urology
巻(号)
191(4)
ページ
932-936
抄録
Purpose: We determined prognostic factors associated with prolonged survival after metastasectomy for urothelial carcinoma. Materials and Methods: A total of 42 patients who underwent resection of urothelial carcinoma metastases with curative intent at 4 Japanese university hospitals were included in analysis. Of the patients 41 of 42 underwent systemic chemotherapy before and/or after metastasectomy. Overall survival was analyzed using the Kaplan-Meier method. The relationship between clinical characteristics and survival was analyzed using the log rank test. Results: Metastasectomy included lymph node dissection in 20 cases, pulmonary resection in 12, pelvic exenteration in 3, resection of local recurrence in 2, resection of subcutaneous metastasis in 2, liver resection in 1 and other in 2. Median overall survival was 29 months (IQR 19-80) from the initiation of treatment for metastases and 26 months (IQR 11-90) from metastasectomy. The overall 5-year survival rate after metastasectomy was 31%. On univariate analysis patients treated with metastasectomy for a solitary lung or solitary lymph node metastasis had significantly longer survival than the others who underwent metastasectomy (81 vs 19 months, log rank test p = 0.0296). Conclusions: Long-term cancer control could be achieved in a subgroup of patients who undergo metastasectomy, especially those with a solitary lung or solitary lymph node metastasis.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
PISSN
0022-5347
EISSN
1527-3792
NCID
AA00708666
関連情報
PMID
24211599
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1016/j.juro.2013.11.004