Human intestinal spirochetosis is significantly associated with sessile serrated adenomas/polyps

Omori, Saori; Mabe, Katsuhiro; Hatanaka, Kanako; Ono, Masayoshi; Matsumoto, Mio; Takahashi, Masakazu; Yoshida, Takeshi; Ono, Shoko; Shimizu, Yuichi; Sugai, Nozomi; Suzuki, Akira; Katsuki, Shinichi; Fujii, Takahiro; Kato, Mototsugu; Asaka, Masahiro; Sakamoto, Naoya

Human intestinal spirochetosis is significantly associated with sessile serrated adenomas/polyps

Omori, Saori; Mabe, Katsuhiro; Hatanaka, Kanako et al.

Pathology, Research and Practice, 2014, 210(7), 440-443

Permalink : https://hdl.handle.net/2115/56700

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アクセス権	open access
URI	https://hdl.handle.net/2115/56700
タイトル	Human intestinal spirochetosis is significantly associated with sessile serrated adenomas/polyps
著者	Omori, Saori ; Mabe, Katsuhiro ; Hatanaka, Kanako ; Ono, Masayoshi ; Matsumoto, Mio ; Takahashi, Masakazu ; Yoshida, Takeshi ; Ono, Shoko ; Shimizu, Yuichi ; Sugai, Nozomi ; Suzuki, Akira ; Katsuki, Shinichi ; Fujii, Takahiro ; Kato, Mototsugu ; Asaka, Masahiro ; Sakamoto, Naoya
著者名 Omori, Saori
著者名 Mabe, Katsuhiro
著者名 Hatanaka, Kanako
著者名 Ono, Masayoshi
著者名 Matsumoto, Mio
著者名 Takahashi, Masakazu
著者名 Yoshida, Takeshi
著者名 Ono, Shoko
e-Rad_Researcher 90333608 著者名 Shimizu, Yuichi
著者名 Sugai, Nozomi
著者名 Suzuki, Akira
著者名 Katsuki, Shinichi
著者名 Fujii, Takahiro
e-Rad_Researcher 60271673 著者名 Kato, Mototsugu
e-Rad_Researcher 10113507 著者名 Asaka, Masahiro
e-Rad_Researcher 10334418 著者名 Sakamoto, Naoya
言語	英語
キーワード	Human intestinal spirochetosis
	Sessile serrated adenoma/polyps
	Serrated lesion
発行日	2014-07
出版者	Elsevier
収録物名	Pathology, Research and Practice
巻(号)	210(7)
ページ	440-443
抄録	It remains unclear whether or not human intestinal spirochetosis (HIS) has any associated symptoms or lesions. In this study, we assessed the prevalence of HIS in sessile serrated adenomas/polyps (SSA/Ps) and their possible association. Following identification of early cecal cancer with SSA/P accompanied by a colonization of HIS, we went on to conduct a retrospective case-control study using endoscopically resected SSA/P specimens to examine the frequency of HIS infection in SSA/Ps. Nineteen SSA/P cases and 172 controls were obtained. The rate of HIS infection was significantly higher at 52.6% (10/19) in the SSA/P cases compared to the controls at 8.1% (14/172). Our SSA/P series were associated with a remarkably higher rate of HIS than controls or than previously reported. This is the first report to provide evidence for potential association between HIS and SSA/Ps. (C) 2014 Elsevier GmbH. All rights reserved.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0344-0338
NCID	AA00769966
関連情報	PMID 24767254
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.prp.2014.03.007