Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy

Sakashita, Tomohiro; Homma, Akihiro; Hatakeyama, Hiromitsu; Kano, Satoshi; Mizumachi, Takatsugu; Furusawa, Jun; Yoshida, Daisuke; Fujima, Noriyuki; Onimaru, Rikiya; Tsuchiya, Kazuhiko; Yasuda, Koichi; Shirato, Hiroki; Suzuki, Fumiyuki; Fukuda, Satoshi

Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy

Sakashita, Tomohiro; Homma, Akihiro; Hatakeyama, Hiromitsu et al.

The British journal of oral & maxillofacial surgery, 2014, 52(4), 323-328

Permalink : https://hdl.handle.net/2115/57079

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アクセス権	open access
URI	https://hdl.handle.net/2115/57079
タイトル	Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy
著者	Sakashita, Tomohiro ; Homma, Akihiro ; Hatakeyama, Hiromitsu ; Kano, Satoshi ; Mizumachi, Takatsugu ; Furusawa, Jun ; Yoshida, Daisuke ; Fujima, Noriyuki ; Onimaru, Rikiya ; Tsuchiya, Kazuhiko ; Yasuda, Koichi ; Shirato, Hiroki ; Suzuki, Fumiyuki ; Fukuda, Satoshi
e-Rad_Researcher 30455654 著者名 Sakashita, Tomohiro
e-Rad_Researcher 30312359 著者名 Homma, Akihiro
e-Rad_Researcher 10455652 著者名 Hatakeyama, Hiromitsu
e-Rad_Researcher 00374421 著者名 Kano, Satoshi
著者名 Mizumachi, Takatsugu
著者名 Furusawa, Jun
著者名 Yoshida, Daisuke
e-Rad_Researcher 80431360 著者名 Fujima, Noriyuki
e-Rad_Researcher 80374461 著者名 Onimaru, Rikiya
e-Rad_Researcher 60580892 著者名 Tsuchiya, Kazuhiko
e-Rad_Researcher 00431362 著者名 Yasuda, Koichi
e-Rad_Researcher 20187537 著者名 Shirato, Hiroki
著者名 Suzuki, Fumiyuki
e-Rad_Researcher 20125347 著者名 Fukuda, Satoshi
言語	英語
キーワード	Maxillary sinus cancer
	Salvage surgery
	Squamous cell carcinoma
	Chemotherapy
	Radiotherapy
	Intra-arterial
発行日	2014-04
出版者	Elsevier
収録物名	The British journal of oral & maxillofacial surgery
巻(号)	52(4)
ページ	323-328
抄録	Our aim was to evaluate the feasibility of salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy. We retrospectively analysed the records of 61 patients with cancer of the maxillary sinus who were treated in this way. Chemotherapy comprised 100-120 mg/m(2) superselective intra-arterial infusions of cisplatin given a median of 4 times weekly (range 2-5). Concurrent radiotherapy was given in a median dose of 65 Gy (range 24-70 Gy). Persistent or recurrent cancer of the maxillary sinus was found in 17 patients, of whom 11 had salvage surgery. The disease was controlled in 8 of the 11, and 7 of the 11 survived with no evidence of disease. Their 5-year overall survival was 61%. Two of the 11 developed serious operative complications. Salvage surgery for patients with persistent or recurrent cancer of the maxillary sinus treated by superselective chemoradiotherapy is both safe and successful. Salvage surgery is a good option when this sort of persistent or recurrent cancer is followed up after the regimen of chemoradiotherapy described. (C) 2014 Elsevier Inc. All rights reserved.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	1532-1940
関連情報	PMID 24582012
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.bjoms.2014.01.018