Pathogenicity of border disease virus FNK2012-1 strain isolated from a pig in the natural host, sheep

Tamura, Tomokazu; Mine, Junki; Torii, Shiho et al.

Journal of veterinary medical science, 2015, 77(3), 341-343

Permalink : https://hdl.handle.net/2115/59104

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アクセス権
open access
URI
https://hdl.handle.net/2115/59104
タイトル
Pathogenicity of border disease virus FNK2012-1 strain isolated from a pig in the natural host, sheep
著者
Tamura, Tomokazu ; Mine, Junki ; Torii, Shiho ; Fujimoto, Yuri ; Okamatsu, Masatoshi ; Sakoda, Yoshihiro
著者名
Tamura, Tomokazu
著者名
Mine, Junki
著者名
Torii, Shiho
著者名
Fujimoto, Yuri
e-Rad_Researcher
00507163
著者名
Okamatsu, Masatoshi
e-Rad_Researcher
40333637
著者名
Sakoda, Yoshihiro
言語
英語
キーワード
border disease virus
host
pathogenicity
sheep
発行日
2015-03
出版者
The Journal of Veterinary Medical Science
収録物名
Journal of veterinary medical science
巻(号)
77(3)
ページ
341-343
抄録
A first isolation of border disease virus (BDV) in Japan was from a pig on a farm without keeping any ruminants. Our previous study showed that this BDV, termed the FNK2012-1 strain, replicated inefficiently in swine-derived cells compared with those of ruminant origin. Pigs inoculated with this virus showed neither clinical symptoms nor viremia. In this study, we evaluated the pathogenicity of the FNK2012-1 strain in sheep, its natural host. The inoculated sheep showed clinical symptoms and transient viremia. Seroconversion was observed in the inoculated sheep. These results suggest that the FNK2012-1 strain was introduced from sheep and has not yet adapted to swine. Therefore, surveillance of border disease in Japan is necessary among both the swine and ruminant populations.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
PISSN
0916-7250
EISSN
1347-7439
NCID
AA10796138
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.1292/jvms.14-0434