Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering

Nishida, Erika; Miyaji, Hirofumi; Takita, Hiroko; Kanayama, Izumi; Tsuji, Maiko; Akasaka, Tsukasa; Sugaya, Tsutomu; Sakagami, Ryuji; Kawanami, Masamitsu

Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering

Nishida, Erika; Miyaji, Hirofumi; Takita, Hiroko et al.

Japanese Journal of Applied Physics, 2014, 53(6S), 06JD04

Permalink : https://hdl.handle.net/2115/59234

このアイテムのアクセス数:1,080件（2026-10-09 17:40 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
15.6.6 JJAP	pdf	1.29 MB	1,463

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/59234
タイトル	Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering
著者	Nishida, Erika ; Miyaji, Hirofumi ; Takita, Hiroko ; Kanayama, Izumi ; Tsuji, Maiko ; Akasaka, Tsukasa ; Sugaya, Tsutomu ; Sakagami, Ryuji ; Kawanami, Masamitsu
著者名 Nishida, Erika
e-Rad_Researcher 50372256 著者名 Miyaji, Hirofumi
e-Rad_Researcher 30125330 著者名 Takita, Hiroko
著者名 Kanayama, Izumi
著者名 Tsuji, Maiko
e-Rad_Researcher 00360917 著者名 Akasaka, Tsukasa
e-Rad_Researcher 10211301 著者名 Sugaya, Tsutomu
e-Rad_Researcher 50215612 著者名 Sakagami, Ryuji
e-Rad_Researcher 10133761 著者名 Kawanami, Masamitsu
言語	英語
発行日	2014-06
出版者	The Japan Society of Applied Physics
出版者	応用物理学会
収録物名	Japanese Journal of Applied Physics
巻(号)	53(6S)
ページ	06JD04
抄録	Carbon-based nanomaterials are being investigated for biomedical applications. Graphene oxide (GO), a monolayer of carbon, holds promise as a tissue engineering substrate due to its unique physicochemical properties. The aim of this study was to evaluate the effect of a GO coating on cell proliferation and differentiation in vitro. We also assessed the bioactivities of collagen scaffolds coated with different concentrations of GO in rats. The results showed that GO affects both cell proliferation and differentiation, and improves the properties of collagen scaffolds. Subcutaneous implant tests showed that low concentrations of GO scaffold enhances cell in-growth and is highly biodegradable, whereas high concentrations of GO coating resulted in adverse biological effects. Consequently, scaffolds modified with a suitable concentration of GO are useful as a bioactive material for tissue engineering.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	© 2014 The Japan Society of Applied Physics
PISSN	0021-4922
EISSN	1347-4065
NCID	AA12295836
関連情報	NAID 150000109415
関連情報	URI http://iopscience.iop.org/1347-4065/53/6S
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.7567/JJAP.53.06JD04