Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure

Terui, Hiroya; Konno, Satoshi; Kaga, Kichizo; Matsuno, Yoshihiro; Hatanaka, Kanako C.; Kanno, Hiromi; Moriyama, Hiroshi; Uo, Motohiro; Nishimura, Masaharu

Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure

Terui, Hiroya; Konno, Satoshi; Kaga, Kichizo et al.

Journal of occupational medicine and toxicology, 2015, 10, 29

Permalink : https://hdl.handle.net/2115/59819

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アクセス権	open access
URI	https://hdl.handle.net/2115/59819
タイトル	Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure
著者	Terui, Hiroya ; Konno, Satoshi ; Kaga, Kichizo ; Matsuno, Yoshihiro ; Hatanaka, Kanako C. ; Kanno, Hiromi ; Moriyama, Hiroshi ; Uo, Motohiro ; Nishimura, Masaharu
著者名 Terui, Hiroya
e-Rad_Researcher 20399835 著者名 Konno, Satoshi
e-Rad_Researcher 80224335 著者名 Kaga, Kichizo
著者名 Matsuno, Yoshihiro
著者名 Hatanaka, Kanako C.
著者名 Kanno, Hiromi
著者名 Moriyama, Hiroshi
e-Rad_Researcher 20242042 著者名 Uo, Motohiro
e-Rad_Researcher 00208224 著者名 Nishimura, Masaharu
言語	英語
キーワード	Hard metal lung disease
	Pulmonary function
	Dust exposure
	Avoidance
	BALF
発行日	2015-08-05
出版者	BioMed Central
収録物名	Journal of occupational medicine and toxicology
巻(号)	10
ページ	29
抄録	We present herein two cases of hard metal lung disease (HMLD) with distinct pathological findings. Both cases showed gradual improvements in pulmonary function over a period of a few years (Case 1: 30 months; Case 2: 12 months) after the avoidance of dust exposure, while improvements on high-resolution computed tomography were modest. The increased lymphocytes and decreased CD4/CD8 ratio in BALF observed at initial diagnosis normalized after the avoidance of dust exposure in one case. To the best of our knowledge, this is the first report demonstrating continual follow-up of pulmonary function and radiographic findings, and a comparison of BALF findings before and after avoidance of hard metal dust exposure.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	1745-6673
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1186/s12995-015-0070-9