Model for calcium-mediated reduction of structural fluctuations in epidermis

Kobayashi, Yasuaki; Kitahata, Hiroyuki; Nagayama, Masaharu

Physical review E, 2015, 92(2), 022709-1-022709-7

Permalink : https://hdl.handle.net/2115/59887

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ファイル	フォーマット	サイズ	閲覧回数	説明
PhysRevE.92.022709	pdf	480 KB	807

アクセス権	open access
URI	https://hdl.handle.net/2115/59887
タイトル	Model for calcium-mediated reduction of structural fluctuations in epidermis
著者	Kobayashi, Yasuaki ; Kitahata, Hiroyuki ; Nagayama, Masaharu
著者名 Kobayashi, Yasuaki
e-Rad_Researcher 20378532 著者名 Kitahata, Hiroyuki
e-Rad_Researcher 20314289 著者名 Nagayama, Masaharu
言語	英語
発行日	2015-08-13
出版者	American Physical Society
収録物名	Physical review E
巻(号)	92(2)
ページ	022709-1-022709-7
抄録	We propose a reaction-advection-diffusion model of epidermis consisting of two variables, the degree of differentiation and the calcium ion concentration, where calcium ions enhance differentiation. By analytically and numerically investigating this system, we show that a calcium localization layer formed beneath the stratum corneum helps reduce spatiotemporal fluctuations of the structure of the stratum corneum. In particular, spatially or temporally small-scale fluctuations in the lower structure are suppressed and do not affect the upper structure, due to acceleration of differentiation by calcium ions. Analytical expressions for the reduction rate of fluctuation amplitudes are shown.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	©2015 American Physical Society
PISSN	1539-3755
関連情報	PMID 26382434
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1103/PhysRevE.92.022709