Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation

Harada, Yae; Hirata, Kenji; Nakayama, Naoki; Yamaguchi, Shigeru; Yoshida, Michiharu; Onodera, Shunsuke; Manabe, Osamu; Shiga, Tohru; Terae, Satoshi; Shirato, Hiroki; Tamaki, Nagara

Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation

Harada, Yae; Hirata, Kenji; Nakayama, Naoki et al.

Acta radiologica open, 2015, 4(6), 2058460115584112

Permalink : https://hdl.handle.net/2115/60585

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アクセス権	open access
URI	https://hdl.handle.net/2115/60585
タイトル	Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation
著者	Harada, Yae ; Hirata, Kenji ; Nakayama, Naoki ; Yamaguchi, Shigeru ; Yoshida, Michiharu ; Onodera, Shunsuke ; Manabe, Osamu ; Shiga, Tohru ; Terae, Satoshi ; Shirato, Hiroki ; Tamaki, Nagara
著者名 Harada, Yae
e-Rad_Researcher 30431365 著者名 Hirata, Kenji
e-Rad_Researcher 40421961 著者名 Nakayama, Naoki
著者名 Yamaguchi, Shigeru
著者名 Yoshida, Michiharu
著者名 Onodera, Shunsuke
e-Rad_Researcher 40443957 著者名 Manabe, Osamu
e-Rad_Researcher 80374495 著者名 Shiga, Tohru
e-Rad_Researcher 40240634 著者名 Terae, Satoshi
e-Rad_Researcher 20187537 著者名 Shirato, Hiroki
e-Rad_Researcher 30171888 著者名 Tamaki, Nagara
言語	英語
キーワード	Intracranial arteriovenous malformation
	stereotactic radiosurgery
	radiation-induced necrosis
	brain edema
	F-18 fluorodeoxyglucose
	positron emission tomography
発行日	2015-06-29
出版者	SAGE Publications
収録物名	Acta radiologica open
巻(号)	4(6)
ページ	2058460115584112
抄録	A 55-year-old woman underwent radiosurgery for a left cerebral hemisphere arteriovenous malformation (AVM) and developed radiation-induced necrosis causing a massive edema in the surrounding brain tissues. Despite various therapies, the edema expanded to the ipsilateral hemisphere and induced neurological symptoms. The radiation-induced necrotic lesion was surgically removed 4 years after radiosurgery. While the preoperative FDG PET revealed severe hypometabolism in the left cerebrum, the necrotomy significantly ameliorated the brain edema, glucose metabolism (postoperative FDG PET), and symptoms. This case indicates that radiation necrosis-induced neurological deficits may be associated with brain edema and hypometabolism, which could be reversed by appropriate necrotomy.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial 3.0 Unported
PISSN	2058-4601
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1177/2058460115584112