Orthopoxvirus infection among wildlife in Zambia

Orba, Yasuko; Sasaki, Michihito; Yamaguchi, Hiroki; Ishii, Akihiro; Thomas, Yuka; Ogawa, Hirohito; Hang'ombe, Bernard M.; Mweene, Aaron S.; Morikawa, Shigeru; Saijo, Masayuki; Sawa, Hirofumi

Orthopoxvirus infection among wildlife in Zambia

Orba, Yasuko; Sasaki, Michihito; Yamaguchi, Hiroki et al.

Journal of General Virology, 2015, 96(2), 390-394

Permalink : https://hdl.handle.net/2115/60631

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/60631
タイトル	Orthopoxvirus infection among wildlife in Zambia
著者	Orba, Yasuko ; Sasaki, Michihito ; Yamaguchi, Hiroki ; Ishii, Akihiro ; Thomas, Yuka ; Ogawa, Hirohito ; Hang'ombe, Bernard M. ; Mweene, Aaron S. ; Morikawa, Shigeru ; Saijo, Masayuki ; Sawa, Hirofumi
e-Rad_Researcher 60507169 著者名 Orba, Yasuko
e-Rad_Researcher 70609403 著者名 Sasaki, Michihito
著者名 Yamaguchi, Hiroki
e-Rad_Researcher 90421982 著者名 Ishii, Akihiro
著者名 Thomas, Yuka
著者名 Ogawa, Hirohito
著者名 Hang'ombe, Bernard M.
著者名 Mweene, Aaron S.
e-Rad_Researcher 00167686 著者名 Morikawa, Shigeru
e-Rad_Researcher 50300926 著者名 Saijo, Masayuki
e-Rad_Researcher 30292006 著者名 Sawa, Hirofumi
言語	英語
発行日	2015-02
出版者	Society for General Microbiology
収録物名	Journal of General Virology
巻(号)	96(2)
ページ	390-394
抄録	Human monkeypox is a viral zoonosis caused by monkeypox virus, an orthopoxvirus (OPXV). The majority of human monkeypox cases have been reported in moist forested regions in West and Central Africa, particularly in the Democratic Republic of the Congo (DRC). In this study we investigated zoonotic OPXV infection among wild animals in Zambia, which shares a border with DRC, to assess the geographical distribution of OPXV. We screened for OPXV antibodies in sera from non-human primates (NHPs), rodents and shrews by ELISA, and performed real-time PCR to detect OPXV DNA in spleen samples. Serological analysis indicated that 38 of 259 (14.7 %) rodents, 14 of 42 (33.3%) shrews and 4 of 188 (2.1 %) NHPs had antibodies against OPXV. The OPXV DNA could not be detected in spleens from any animals tested. Our results indicated that wild animals living in rural human habitation areas of Zambia have been infected with OPXV.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0022-1317
EISSN	1465-2099
NCID	AA00698722
関連情報	PMID 25319753
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1099/vir.0.070219-0