Transcription of 4'-thioDNA templates to natural RNA in vitro and in mammalian cells

Maruyama, Hideto; Furukawa, Kazuhiro; Kamiya, Hiroyuki et al.

Chemical communications, 2015, 51(37), 7887-7890

Permalink : https://hdl.handle.net/2115/60827

このアイテムのアクセス数:960件（2026-08-24 18:02 集計）

ファイル	フォーマット	サイズ	閲覧回数	説明
manuscript	pdf	454 KB	1,057

アクセス権	open access
URI	https://hdl.handle.net/2115/60827
タイトル	Transcription of 4'-thioDNA templates to natural RNA in vitro and in mammalian cells
著者	Maruyama, Hideto ; Furukawa, Kazuhiro ; Kamiya, Hiroyuki ; Minakawa, Noriaki ; Matsuda, Akira
著者名 Maruyama, Hideto
著者名 Furukawa, Kazuhiro
e-Rad_Researcher 10204629 著者名 Kamiya, Hiroyuki
著者名 Minakawa, Noriaki
e-Rad_Researcher 90157313 著者名 Matsuda, Akira
言語	英語
発行日	2015-05-07
出版者	Royal Society of Chemistry
収録物名	Chemical communications
巻(号)	51(37)
ページ	7887-7890
抄録	Synthetic chemically modified nucleic acids, which are compatible with DNA/RNA polymerases, have great potential as a genetic material for synthetic biological studies. A comprehensive analysis of the transcription of 4'-thioDNA templates to natural RNA is herein reported. The modifications of DNA with 2'-deoxy-4'-thionucleosides, so-called 4'-thioDNA, were found to act as templates for transcription with RNA polymerases both in vitro and in mammalian cells.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	1359-7345
関連情報	PMID 25854199
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1039/c4cc08862j