Indications for superselective intra-arterial cisplatin infusion and concomitant radiotherapy in cases of hypopharyngeal cancer

Furusawa, Jun; Homma, Akihiro; Onimaru, Rikiya; Sakashita, Tomohiro; Yoshida, Daisuke; Hatakeyama, Hiromitsu; Mizumachi, Takatsugu; Kano, Satoshi; Tsuchiya, Kazuhiko; Yasuda, Koichi; Shirato, Hiroki; Fukuda, Satoshi

Indications for superselective intra-arterial cisplatin infusion and concomitant radiotherapy in cases of hypopharyngeal cancer

Furusawa, Jun; Homma, Akihiro; Onimaru, Rikiya et al.

Auris nasus larynx, 2015, 42(6), 443-448

Permalink : https://hdl.handle.net/2115/63714

このアイテムのアクセス数:1,141件（2026-08-10 17:26 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
manuscript	pdf	663 KB	1,008

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/63714
タイトル	Indications for superselective intra-arterial cisplatin infusion and concomitant radiotherapy in cases of hypopharyngeal cancer
著者	Furusawa, Jun ; Homma, Akihiro ; Onimaru, Rikiya ; Sakashita, Tomohiro ; Yoshida, Daisuke ; Hatakeyama, Hiromitsu ; Mizumachi, Takatsugu ; Kano, Satoshi ; Tsuchiya, Kazuhiko ; Yasuda, Koichi ; Shirato, Hiroki ; Fukuda, Satoshi
著者名 Furusawa, Jun
e-Rad_Researcher 30312359 著者名 Homma, Akihiro
e-Rad_Researcher 80374461 著者名 Onimaru, Rikiya
e-Rad_Researcher 30455654 著者名 Sakashita, Tomohiro
著者名 Yoshida, Daisuke
e-Rad_Researcher 10455652 著者名 Hatakeyama, Hiromitsu
e-Rad_Researcher 00507577 著者名 Mizumachi, Takatsugu
e-Rad_Researcher 00374421 著者名 Kano, Satoshi
e-Rad_Researcher 60580892 著者名 Tsuchiya, Kazuhiko
e-Rad_Researcher 00431362 著者名 Yasuda, Koichi
e-Rad_Researcher 20187537 著者名 Shirato, Hiroki
e-Rad_Researcher 20125347 著者名 Fukuda, Satoshi
言語	英語
キーワード	Head and neck cancer
	Hypopharyngeal cancer
	Intra-arterial
	Chemotherapy
	Radiotherapy
発行日	2015-12
出版者	Elsevier
収録物名	Auris nasus larynx
巻(号)	42(6)
ページ	443-448
抄録	Objective: We retrospectively assessed the indications for superselective intra-arterial infusion of cisplatin with concomitant radiotherapy (RADPLAT) in patients with hypopharyngeal cancer (HPC). Methods: Between April 2000 and March 2013,41 previously untreated patients received superselective intra-arterial infusion of cisplatin (100-120 mg/m2 per week) with simultaneous intravenous infusions of thiosulfate to neutralize cisplatin toxicity and conventional radiotherapy (65-70 Gy). Results: During the median follow-up period of 5.5 years, a statistically significant difference in the 5-year overall survival was noted between patients with N0-1 (n = 14) and N2b-3 disease (n = 27). One-half of deaths were observed to be the result of distant metastasis. The 5-year local control and overall survival were significantly better in patients with unilateral than in those with bilateral primary tumors. All the patients with T4b disease (n = 3) died of disease within 2 years. Conclusion: Indications for RADPLAT in patients with HPC were defined as patients with unilateral tumors staged as T3-4a and N0-1.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	0385-8146
関連情報	PMID 25933585
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.anl.2015.04.003