Risk Factors for Lower Urinary Tract Dysfunction and Symptoms After Successful Renal Transplantation

Mitsui, Takahiko; Moriya, Kimihiko; Morita, Ken; Iwami, Daiki; Kitta, Takeya; Kanno, Yukiko; Takeda, Masayuki; Shinohara, Nobuo

Risk Factors for Lower Urinary Tract Dysfunction and Symptoms After Successful Renal Transplantation

Mitsui, Takahiko; Moriya, Kimihiko; Morita, Ken et al.

Annals of transplantation, 2015, 20, 757-763

Permalink : https://hdl.handle.net/2115/64543

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アクセス権	open access
URI	https://hdl.handle.net/2115/64543
タイトル	Risk Factors for Lower Urinary Tract Dysfunction and Symptoms After Successful Renal Transplantation
著者	Mitsui, Takahiko ; Moriya, Kimihiko ; Morita, Ken ; Iwami, Daiki ; Kitta, Takeya ; Kanno, Yukiko ; Takeda, Masayuki ; Shinohara, Nobuo
e-Rad_Researcher 90421966 著者名 Mitsui, Takahiko
e-Rad_Researcher 20374233 著者名 Moriya, Kimihiko
著者名 Morita, Ken
e-Rad_Researcher 80581115 著者名 Iwami, Daiki
e-Rad_Researcher 40374441 著者名 Kitta, Takeya
著者名 Kanno, Yukiko
著者名 Takeda, Masayuki
e-Rad_Researcher 90250422 著者名 Shinohara, Nobuo
言語	英語
キーワード	Diabetes Mellitus
	Kidney Transplantation
	Lower Urinary Tract Symptoms
	Risk Factors
	Urinary Bladder, Overactive
	Urinary Tract Physiological Phenomena
発行日	2015-12-24
出版者	International Scientific Information
収録物名	Annals of transplantation
巻(号)	20
ページ	757-763
抄録	BACKGROUND: We investigated risk factors for lower urinary tract (LUT) dysfunction and LUT symptoms in patients who successfully underwent renal transplantation (RTX). MATERIAL AND METHODS: Ninety-five patients (54 males and 41 females) undergoing RTX (median age: 45 years old) at Hokkaido University Hospital were included in this study. Uroflowmetry (UFM), postvoid residual urine volume (PVR), and 24-h bladder diaries were performed. We analyzed risk factors for voiding dysfunction, urinary frequency, polyuria, nocturia, and nocturnal polyuria after RTX using logistic regression analysis. RESULTS: End-stage renal disease arose from diabetes mellitus in 18 patients (19%). Pre-transplant dialysis had been carried out in 74 patients. Voiding dysfunction as assessed by UFM and PVR was observed in 24 patients (27%). Based on the 24-h bladder diaries, we identified frequent micturition in 29 patients (35%), polyuria in 44 (54%), nocturia in 30 (37%), and nocturnal polyuria in 46 (56%). A multivariable logistic regression analysis revealed that diabetes mellitus, which may cause autonomic disorders, was a risk factor for voiding dysfunction and nocturnal polyuria. A risk factor for frequent micturition and nocturia was older age at RTX. Being female was a risk factor for polyuria, which suggested that fluid intake in relation to body weight was higher in females. CONCLUSIONS: LUT dysfunction and LUT symptoms were not uncommon in patients who successfully underwent RTX. LUT dysfunction and LUT symptoms need to be considered in patients with risk factors such as diabetes mellitus, older age at RTX, and being female, even after successful RTX.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN	1425-9524
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.12659/AOT.895515