Characteristics of patients with liver cancer in the BioBank Japan project

Ukawa, Shigekazu; Okada, Emiko; Nakamura, Koshi; Hirata, Makoto; Nagai, Akiko; Matsuda, Koichi; Yamagata, Zentaro; Kamatani, Yoichiro; Ninomiya, Toshiharu; Kiyohara, Yutaka; Muto, Kaori; Kubo, Michiaki; Nakamura, Yusuke; BioBank Japan Cooperative Hospital Group; Tamakoshi, Akiko

Characteristics of patients with liver cancer in the BioBank Japan project

Ukawa, Shigekazu; Okada, Emiko; Nakamura, Koshi et al.

Journal of epidemiology, 2017, 27(3, Supplement), S43-S48

Permalink : https://hdl.handle.net/2115/65811

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アクセス権	open access
URI	https://hdl.handle.net/2115/65811
タイトル	Characteristics of patients with liver cancer in the BioBank Japan project
著者	Ukawa, Shigekazu ; Okada, Emiko ; Nakamura, Koshi ; Hirata, Makoto ; Nagai, Akiko ; Matsuda, Koichi ; Yamagata, Zentaro ; Kamatani, Yoichiro ; Ninomiya, Toshiharu ; Kiyohara, Yutaka ; Muto, Kaori ; Kubo, Michiaki ; Nakamura, Yusuke ; BioBank Japan Cooperative Hospital Group ; Tamakoshi, Akiko
e-Rad_Researcher 40706751 著者名 Ukawa, Shigekazu
e-Rad_Researcher 00766537 著者名 Okada, Emiko
e-Rad_Researcher 80422898 著者名 Nakamura, Koshi
著者名 Hirata, Makoto
著者名 Nagai, Akiko
e-Rad_Researcher 90401257 著者名 Matsuda, Koichi
著者名 Yamagata, Zentaro
著者名 Kamatani, Yoichiro
著者名 Ninomiya, Toshiharu
著者名 Kiyohara, Yutaka
著者名 Muto, Kaori
e-Rad_Researcher 30442958 著者名 Kubo, Michiaki
e-Rad_Researcher 70217909 著者名 Nakamura, Yusuke
著者名 BioBank Japan Cooperative Hospital Group
e-Rad_Researcher 90236737 著者名 Tamakoshi, Akiko
言語	英語
キーワード	Liver cancer
	Cohort
	Lifestyle
	Tumor biomarkers
	Survival rate
発行日	2017-03
出版者	Elsevier
収録物名	Journal of epidemiology
巻(号)	27(3, Supplement)
ページ	S43-S48
抄録	Background: Liver cancer is the fifth cause of cancer-related deaths in Japan. The BioBank Japan (BBJ) project included 200,000 patients with 47 diseases and samples; their clinical information can be used for further studies. Methods: Patients diagnosed with liver cancer (n = 1733; 1316 men, 417 women) were included. Histology, patient characteristics, clinical characteristics, and causes of death were collected. Cumulative and relative survival rates for liver cancer were calculated. Results: Of the 1354 patients with available liver cancer histology, 91.9% had hepatocellular carcinoma (HCC). Compared with the National Health and Nutrition Examination Survey, greater proportions of the male patients in this cohort were daily alcohol consumers (26%), and a greater proportion of the men was overweight/obesity (22%). Although Japan is the only Asian country with a predominance of hepatitis C virus (HCV)-related HCC, the prevalence of HCV infection (44%) was lower than that in a previous study. The 3-, 5-, and 10-year cumulative survival rates were 57%, 47%, and 25% in men, respectively, and 49%, 41%, and 27% in women, respectively. Conclusions: The present results provide an overview of the patients with liver cancer in the BBJ project. We are planning further analyses combined with various high-throughput ‘omics’ technologies.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN	0917-5040
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1016/j.je.2016.12.007