Predictors of folate status among pregnant Japanese women : the Hokkaido Study on Environment and Children's Health, 2002-2012

Yila, Thamar A.; Araki, Atsuko; Sasaki, Seiko; Miyashita, Chihiro; Itoh, Kumiko; Ikeno, Tamiko; Yoshioka, Eiji; Kobayashi, Sumitaka; Goudarzi, Houman; Baba, Toshiaki; Braimoh, Titilola; Minakami, Hisanori; Endo, Toshiaki; Sengoku, Kazuo; Kishi, Reiko

Predictors of folate status among pregnant Japanese women : the Hokkaido Study on Environment and Children's Health, 2002-2012

Yila, Thamar A.; Araki, Atsuko; Sasaki, Seiko et al.

British Journal of Nutrition, 2016, 115(12), 2227-2235

Permalink : https://hdl.handle.net/2115/65838

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アクセス権	open access
URI	https://hdl.handle.net/2115/65838
タイトル	Predictors of folate status among pregnant Japanese women : the Hokkaido Study on Environment and Children's Health, 2002-2012
著者	Yila, Thamar A. ; Araki, Atsuko ; Sasaki, Seiko ; Miyashita, Chihiro ; Itoh, Kumiko ; Ikeno, Tamiko ; Yoshioka, Eiji ; Kobayashi, Sumitaka ; Goudarzi, Houman ; Baba, Toshiaki ; Braimoh, Titilola ; Minakami, Hisanori ; Endo, Toshiaki ; Sengoku, Kazuo ; Kishi, Reiko
著者名 Yila, Thamar A.
e-Rad_Researcher 00619885 著者名 Araki, Atsuko
e-Rad_Researcher 30448831 著者名 Sasaki, Seiko
e-Rad_Researcher 70632389 著者名 Miyashita, Chihiro
著者名 Itoh, Kumiko
e-Rad_Researcher 80569715 著者名 Ikeno, Tamiko
e-Rad_Researcher 70435957 著者名 Yoshioka, Eiji
e-Rad_Researcher 10733371 著者名 Kobayashi, Sumitaka
e-Rad_Researcher 40713607 著者名 Goudarzi, Houman
著者名 Baba, Toshiaki
著者名 Braimoh, Titilola
e-Rad_Researcher 40102256 著者名 Minakami, Hisanori
e-Rad_Researcher 90213595 著者名 Endo, Toshiaki
e-Rad_Researcher 30163124 著者名 Sengoku, Kazuo
e-Rad_Researcher 80112449 著者名 Kishi, Reiko
言語	英語
キーワード	Folate status
	Pregnancy
	Tobacco smoking
	Hokkaido Study on Environment and Children’s Health
発行日	2016-06
出版者	Cambridge University Press
収録物名	British Journal of Nutrition
巻(号)	115(12)
ページ	2227-2235
抄録	The International Clearinghouse for Birth Defects, Surveillance and Research reports a rise in the prevalence rate of spina bifida in Japan. We determined first-trimester folate status of Hokkaido women and identified potential predictors. Participants were 15 266 pregnant women of the Hokkaido Study on Environment and Children’s Health Cohort. Data were extracted from self-reported questionnaires and biochemical assay results. Demographic determinants of low folate status were younger maternal age (adjusted OR (AOR) 1·48; 95 % CI 1·32, 1·66), lower educational level (AOR 1·27; 95 % CI 1·17, 1·39) and lower annual income (AOR 1·11; 95 % CI 1·01, 1·22). Plasma cotinine concentrations of 1·19-65·21 nmol/l increased the risk of low folate status (AOR 1·20; 95 % CI 1·10, 1·31) and concentrations >65·21 nmol/l further increased the risk (AOR 1·91; 95 % CI 1·70, 2·14). The most favourable predictor was use of folic acid (FA) supplements (AOR 0·19; 95 % CI 0·17, 0·22). Certain socio-demographic factors influence folate status among pregnant Japanese women. Modifiable negative and positive predictors were active and passive tobacco smoking and use of FA supplements. Avoiding both active and passive tobacco smoking and using FA supplements could improve the folate status of Japanese women.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	© The Authors 2016
PISSN	0007-1145
EISSN	1475-2662
関連情報	PMID 27121118
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1017/S0007114516001628