Optimization and evaluation of multiple gating beam delivery in a synchrotron-based proton beam scanning system using a real-time imaging technique

Yamada, Takahiro; Miyamoto, Naoki; Matsuura, Taeko; Takao, Seishin; Fujii, Yusuke; Matsuzaki, Yuka; Koyano, Hidenori; Umezawa, Masumi; Nihongi, Hideaki; Shimizu, Shinichi; Shirato, Hiroki; Umegaki, Kikuo

Optimization and evaluation of multiple gating beam delivery in a synchrotron-based proton beam scanning system using a real-time imaging technique

Yamada, Takahiro; Miyamoto, Naoki; Matsuura, Taeko et al.

Physica medica : European journal of medical physics, 2016, 32(7), 932-937

Permalink : https://hdl.handle.net/2115/66410

このアイテムのアクセス数:1,048件（2026-08-24 16:08 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
PhysicaMedica32_932	pdf	513 KB	974

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/66410
タイトル	Optimization and evaluation of multiple gating beam delivery in a synchrotron-based proton beam scanning system using a real-time imaging technique
著者	Yamada, Takahiro ; Miyamoto, Naoki ; Matsuura, Taeko ; Takao, Seishin ; Fujii, Yusuke ; Matsuzaki, Yuka ; Koyano, Hidenori ; Umezawa, Masumi ; Nihongi, Hideaki ; Shimizu, Shinichi ; Shirato, Hiroki ; Umegaki, Kikuo
著者名 Yamada, Takahiro
e-Rad_Researcher 00552879 著者名 Miyamoto, Naoki
e-Rad_Researcher 90590266 著者名 Matsuura, Taeko
e-Rad_Researcher 10614216 著者名 Takao, Seishin
著者名 Fujii, Yusuke
著者名 Matsuzaki, Yuka
著者名 Koyano, Hidenori
著者名 Umezawa, Masumi
著者名 Nihongi, Hideaki
e-Rad_Researcher 50463724 著者名 Shimizu, Shinichi
e-Rad_Researcher 20187537 著者名 Shirato, Hiroki
著者名 Umegaki, Kikuo
言語	英語
キーワード	Tumor tracking
	Spot scanning
	Respiratory motion
	Gated irradiation
発行日	2016-07
出版者	Elsevier
収録物名	Physica medica : European journal of medical physics
巻(号)	32(7)
ページ	932-937
抄録	Purpose: To find the optimum parameter of a new beam control function installed in a synchrotron-based proton therapy system. Methods: A function enabling multiple gated irradiation in the flat top phase has been installed in a real-time-image gated proton beam therapy (RGPT) system. This function is realized by a waiting timer that monitors the elapsed time from the last gate-off signal in the flat top phase. The gated irradiation efficiency depends on the timer value, Tw. To find the optimum Tw value, gated irradiation efficiency was evaluated for each configurable Tw value. 271 gate signal data sets from 58 patients were used for the simulation. Results: The highest mean efficiency 0.52 was obtained in TW = 0.2 s. The irradiation efficiency was approximately 21% higher than at TW = 0 s, which corresponds to ordinary synchrotron operation. The irradiation efficiency was improved in 154 (57%) of the 271 cases. The irradiation efficiency was reduced in 117 cases because the TW value was insufficient or the function introduced an unutilized wait time for the next gate-on signal in the flat top phase. In the actual treatment of a patient with a hepatic tumor at Tw = 0.2 s, 4.48 GyE irradiation was completed within 250 s. In contrast, the treatment time of ordinary synchrotron operation was estimated to be 420 s. Conclusions: The results suggest that the multiple gated-irradiation function has potential to improve the gated irradiation efficiency and to reduce the treatment time.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	1120-1797
関連情報	PMID 27296793
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.ejmp.2016.06.002