The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma

Tsushima, Nayuta; Sakashita, Tomohiro; Homma, Akihiro; Hatakeyama, Hiromitsu; Kano, Satoshi; Mizumachi, Takatsugu; Kakizaki, Tomohiko; Suzuki, Takayoshi; Fukuda, Satoshi

The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma

Tsushima, Nayuta; Sakashita, Tomohiro; Homma, Akihiro et al.

European Archives of Oto-Rhino-Laryngology, 2016, 273(11), 3987-3992

Permalink : https://hdl.handle.net/2115/67500

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アクセス権	open access
URI	https://hdl.handle.net/2115/67500
タイトル	The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma
著者	Tsushima, Nayuta ; Sakashita, Tomohiro ; Homma, Akihiro ; Hatakeyama, Hiromitsu ; Kano, Satoshi ; Mizumachi, Takatsugu ; Kakizaki, Tomohiko ; Suzuki, Takayoshi ; Fukuda, Satoshi
著者名 Tsushima, Nayuta
e-Rad_Researcher 30455654 著者名 Sakashita, Tomohiro
e-Rad_Researcher 30312359 著者名 Homma, Akihiro
e-Rad_Researcher 10455652 著者名 Hatakeyama, Hiromitsu
e-Rad_Researcher 00374421 著者名 Kano, Satoshi
e-Rad_Researcher 00507577 著者名 Mizumachi, Takatsugu
著者名 Kakizaki, Tomohiko
著者名 Suzuki, Takayoshi
e-Rad_Researcher 20125347 著者名 Fukuda, Satoshi
言語	英語
キーワード	Tongue cancer
	Nodal metastasis
	Neck dissection
	Tumor thickness
発行日	2016-11
出版者	Springer
収録物名	European Archives of Oto-Rhino-Laryngology
巻(号)	273(11)
ページ	3987-3992
抄録	Purpose. Prophylactic neck dissection (PND) for patients with clinically N0 (cN0) tongue carcinoma remains controversial. We assessed the efficacy of PND for patients with cN0 tongue squamous cell carcinoma (SCC) and investigated the prognostic role of tumor thickness as assessed by diagnostic imaging in predicting the risk of nodal micrometastasis or late nodal recurrence. Methods. Eighty-eight patients with cN0 tongue carcinomas underwent surgical treatment. Tumor thickness was measured from magnetic resonance (MR) images or computed tomography (CT) scans. Results. The overall survival rates of patients with or without PND were 94% and 81%, respectively (p=0.2857). MR images or CT scans were available for 68 patients. A tumor thickness ≧10mm or ≧5mm did not increase the probability of nodal metastasis, with late nodal metastasis observed in 15% of patients with graphically undetected small tumors. Conclusions. PND appears to have the potential to improve overall survival for patients with cN0 tongue SCC. Careful follow-up management or PND is considered to be needed regardless of tumor thickness in the pre-treatment evaluation.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	The final publication is available at www.springerlink.com
PISSN	0937-4477
関連情報	PMID 27149875
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s00405-016-4077-3