Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros)

Carr, Michael; Kawaguchi, Akira; Sasaki, Michihito; Gonzalez, Gabriel; Ito, Kimihito; Thomas, Yuka; Hang'ombe, Bernard M.; Mweene, Aaron S.; Zhao, Guoyan; Wang, David; Orba, Yasuko; Ishii, Akihiro; Sawa, Hirofumi

Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros)

Carr, Michael; Kawaguchi, Akira; Sasaki, Michihito et al.

Archives of virology, 2016, 162(2), 543-548

Permalink : https://hdl.handle.net/2115/67556

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/67556
タイトル	Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros)
著者	Carr, Michael ; Kawaguchi, Akira ; Sasaki, Michihito ; Gonzalez, Gabriel ; Ito, Kimihito ; Thomas, Yuka ; Hang'ombe, Bernard M. ; Mweene, Aaron S. ; Zhao, Guoyan ; Wang, David ; Orba, Yasuko ; Ishii, Akihiro ; Sawa, Hirofumi
著者名 Carr, Michael
著者名 Kawaguchi, Akira
e-Rad_Researcher 70609403 著者名 Sasaki, Michihito
著者名 Gonzalez, Gabriel
e-Rad_Researcher 60396314 著者名 Ito, Kimihito
著者名 Thomas, Yuka
著者名 Hang'ombe, Bernard M.
著者名 Mweene, Aaron S.
著者名 Zhao, Guoyan
著者名 Wang, David
e-Rad_Researcher 60507169 著者名 Orba, Yasuko
e-Rad_Researcher 90421982 著者名 Ishii, Akihiro
e-Rad_Researcher 30292006 著者名 Sawa, Hirofumi
言語	英語
キーワード	Simian immunodeficiency virus
	SIV
	African green monkey
	Zambia
	Chlorocebus cynosuros
	malbrouck
	next generation sequencing
	virus discovery
発行日	2016-11-01
出版者	Springer
収録物名	Archives of virology
巻(号)	162(2)
ページ	543-548
抄録	To investigate the diversity of simian immunodeficiency virus (SIV) among nonhuman primates (NHPs) in Zambia, next-generation sequencing was performed to determine the complete genome sequence of a novel SIV recovered by co-culturing African green monkey (AGM) peripheral blood lymphocytes with human CD4(+) T-cell lines. We report the first described SIV (SIVagmMAL-ZMB) from a malbrouck (Chlorocebus cynosuros). SIVagmMAL-ZMB was detected by real-time PCR analysis of splenic RNA in 3.2% (3/94) of AGMs and was undetectable in baboons (0/105). SIVagmMAL-ZMB possessed < 80% nucleotide sequence identity to known SIV isolates and was located basally to vervet monkey SIV strains in all phylogenies.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	The final publication is available at Springer via http://dx.doi.org/10.1007/s00128-016-2011-4
PISSN	0304-8608
関連情報	PMID 27804019
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s00705-016-3129-8