A new method to estimate pulmonary vascular resistance using diastolic pulmonary artery-right ventricular pressure gradients derived from continuous-wave Doppler velocity measurements of pulmonary regurgitation

Kaga, Sanae; Mikami, Taisei; Murayama, Michito et al.

International journal of cardiovascular imaging, 2017, 33(1), 31-38

Permalink : https://hdl.handle.net/2115/68252

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アクセス権
open access
URI
https://hdl.handle.net/2115/68252
タイトル
A new method to estimate pulmonary vascular resistance using diastolic pulmonary artery-right ventricular pressure gradients derived from continuous-wave Doppler velocity measurements of pulmonary regurgitation
著者
Kaga, Sanae ; Mikami, Taisei ; Murayama, Michito ; Okada, Kazunori ; Masauzi, Nobuo ; Nakabachi, Masahiro ; Nishino, Hisao ; Yokoyama, Shinobu ; Nishida, Mutsumi ; Hayashi, Taichi ; Murai, Daisuke ; Iwano, Hiroyuki ; Sakakibara, Mamoru ; Yamada, Satoshi ; Tsutsui, Hiroyuki
著者名
Kaga, Sanae
e-Rad_Researcher
90250456
著者名
Mikami, Taisei
著者名
Murayama, Michito
著者名
Okada, Kazunori
著者名
Masauzi, Nobuo
著者名
Nakabachi, Masahiro
著者名
Nishino, Hisao
著者名
Yokoyama, Shinobu
e-Rad_Researcher
90404722
著者名
Nishida, Mutsumi
著者名
Hayashi, Taichi
著者名
Murai, Daisuke
e-Rad_Researcher
50622354
著者名
Iwano, Hiroyuki
著者名
Sakakibara, Mamoru
e-Rad_Researcher
80374320
著者名
Yamada, Satoshi
e-Rad_Researcher
70264017
著者名
Tsutsui, Hiroyuki
言語
英語
キーワード
Pulmonary vascular resistance
Echocardiography
Pulmonary regurgitation
Left heart failure
発行日
2017-01
出版者
Springer
収録物名
International journal of cardiovascular imaging
巻(号)
33(1)
ページ
31-38
抄録
Pulmonary vascular resistance (PVR) is an important hemodynamic parameter in patients with heart failure, especially when the pulmonary arterial pressure is lower due to reduced stroke volume. Several echocardiographic methods to estimate PVR have been proposed, but their applications in patients with organic left-sided heart diseases have been limited. The aim of the present study was to examine the usefulness of our new method to estimate PVR (PVRPR) based on the continuous-wave Doppler velocity measurements of pulmonary regurgitation in these patients. In 43 patients who underwent right heart catheterization, PVRPR was calculated as the difference between the Doppler-derived early- and end-diastolic pulmonary artery (PA)-right ventricular (RV) pressure gradients divided by the cardiac output measured in the left ventricular outflow tract by echocardiography. The PVRPR correlated well with invasive PVR (PVRCATH) (r = 0.81, p < 0.001) without any fixed bias in Bland-Altman analysis. The conventional echocardiographic PVRs showed inadequate correlations with PVRCATH, or a obvious overestimation of PVRCATH. In the receiver operating characteristic analyses to determine the patients with abnormal elevation of PVRCATH (> 3 Wood units, WU), the area under the curve was the greatest for PVRPR (0.964) compared to the conventional PVRs (0.649-0.839). PVRPR had 83 % sensitivity and 100 % specificity at the optimal cut-off value of 3.10 WU in identifying patients with PVRCATH > 3 WU. Our simple and theoretical PVRPR is useful for the noninvasive estimation of PVR.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
This is a post-peer-review, pre-copyedit version of an article published in International journal of cardiovascular imaging. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10554-016-0965-2
PISSN
1569-5794
EISSN
1875-8312
NCID
AA11582413
関連情報
PMID
27576320
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s10554-016-0965-2