Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection

Yoshida, Tadashi; Homma, Shigenori; Shibasaki, Susumu; Shimokuni, Tatsushi; Sakihama, Hideyasu; Takahashi, Norihiko; Kawamura, Hideki; Taketomi, Akinobu

Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection

Yoshida, Tadashi; Homma, Shigenori; Shibasaki, Susumu et al.

Surgery today, 2017, 47(2), 174-181

Permalink : https://hdl.handle.net/2115/68259

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アクセス権	open access
URI	https://hdl.handle.net/2115/68259
タイトル	Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection
著者	Yoshida, Tadashi ; Homma, Shigenori ; Shibasaki, Susumu ; Shimokuni, Tatsushi ; Sakihama, Hideyasu ; Takahashi, Norihiko ; Kawamura, Hideki ; Taketomi, Akinobu
e-Rad_Researcher 70772333 著者名 Yoshida, Tadashi
e-Rad_Researcher 30533674 著者名 Homma, Shigenori
著者名 Shibasaki, Susumu
著者名 Shimokuni, Tatsushi
e-Rad_Researcher 50533676 著者名 Sakihama, Hideyasu
著者名 Takahashi, Norihiko
e-Rad_Researcher 70645960 著者名 Kawamura, Hideki
e-Rad_Researcher 70363364 著者名 Taketomi, Akinobu
言語	英語
キーワード	Anesthesia
	Laparoscopy
	Colon
発行日	2017-02
出版者	Springer
収録物名	Surgery today
巻(号)	47(2)
ページ	174-181
抄録	Purpose: Effective postoperative analgesia is essential to a patient’s recovery after laparoscopic colon resection (LCR). We introduce a new analgesic protocol using fentanyl plus celecoxib following LCR. Methods: The subjects of this retrospective comparative study were 137 patients who underwent LCR, 63 of whom were treated with 72 h of epidural anesthesia (group E), and 74 of whom were treated with 24 h of fentanyl intravenous injection followed by 7 days of oral celecoxib (group FC). We evaluated the safety and efficacy of this new protocol. Results: The combination of fentanyl and celecoxib maintained a low postoperative pain score (<1.5, evaluated by the FACES Pain Scale) and reduced the need for rescue analgesic drugs for 7 days (groups E vs. FC: 5.39 ± 3.77 vs. 2.79 ± 2.92, p < 0.001). The postoperative hospital stay was almost equal for the two groups (E vs. FC: 11.1 ± 4.5 vs. 10.3 ± 4.8 days, p = 0.315). The operating room stay other than for surgery was significantly shorter for group FC (E vs. FC: 128.7 ± 30.5 vs. 107.2 ± 17.0 min, p < 0.001). Neither group experienced complications, apart from one group FC patient, who suffered transient nausea and vertigo. Conclusions: The new analgesic protocol using fentanyl plus celecoxib is an effective and time-saving strategy for LCR.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	The final publication is available at Springer via http://dx.doi.org/10.1007/s00595-016-1356-y
PISSN	0941-1291
関連情報	PMID 27194126
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s00595-016-1356-y