Primary malignant melanoma of the esophagus treated with subtotal esophagectomy : a case report

Kuwabara, Shota; Ebihara, Yuma; Nakanishi, Yoshitsugu; Asano, Toshimichi; Noji, Takehiro; Kurashima, Yo; Murakami, Soichi; Nakamura, Toru; Tsuchikawa, Takahiro; Okamura, Keisuke; Shichinohe, Toshiaki; Hirano, Satoshi

Primary malignant melanoma of the esophagus treated with subtotal esophagectomy : a case report

Kuwabara, Shota; Ebihara, Yuma; Nakanishi, Yoshitsugu et al.

BMC surgery, 2017, 17, 122

Permalink : https://hdl.handle.net/2115/68335

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アクセス権	open access
URI	https://hdl.handle.net/2115/68335
タイトル	Primary malignant melanoma of the esophagus treated with subtotal esophagectomy : a case report
著者	Kuwabara, Shota ; Ebihara, Yuma ; Nakanishi, Yoshitsugu ; Asano, Toshimichi ; Noji, Takehiro ; Kurashima, Yo ; Murakami, Soichi ; Nakamura, Toru ; Tsuchikawa, Takahiro ; Okamura, Keisuke ; Shichinohe, Toshiaki ; Hirano, Satoshi
著者名 Kuwabara, Shota
e-Rad_Researcher 50632981 著者名 Ebihara, Yuma
著者名 Nakanishi, Yoshitsugu
著者名 Asano, Toshimichi
e-Rad_Researcher 10739296 著者名 Noji, Takehiro
e-Rad_Researcher 40374350 著者名 Kurashima, Yo
著者名 Murakami, Soichi
e-Rad_Researcher 70645796 著者名 Nakamura, Toru
e-Rad_Researcher 50507572 著者名 Tsuchikawa, Takahiro
著者名 Okamura, Keisuke
e-Rad_Researcher 70374353 著者名 Shichinohe, Toshiaki
e-Rad_Researcher 50322813 著者名 Hirano, Satoshi
言語	英語
キーワード	Esophagus
	Melanoma
	Pathology
	Treatment
	Prognosis
発行日	2017-12-02
出版者	BioMed Central
収録物名	BMC surgery
巻(号)	17
ページ	122
抄録	Background: Primary malignant melanoma of the esophagus (PMME) is a rare disease with a poor prognosis. There are few reports of early-stage cases in which tumor invasion reached the lamina propria or muscularis mucosae, as in the present case. A standard treatment for early-stage PMME has not yet been established. The present study aimed to summarize previous reports and to discuss the indications for surgical treatment of early-stage primary malignant melanoma of the esophagus. Case presentation: A 70-year-old woman with PMME was referred to our hospital. She underwent thoracoscopic and laparoscopic subtotal esophagectomy with lymphadenectomy. The resected specimen showed melanocytosis and junctional activity. Melanoma-specific antigens melan-A, S-100, and HMB45 were detected by immunohistochemical staining. The pathological diagnosis was pT1a-MM, pN0, pM0, and pStage IA. She remains alive without evidence of recurrence 39 months later. Conclusion: Subtotal esophagectomy with regional radical lymphadenectomy could be recommended to patients with early-stage primary malignant melanoma of the esophagus, and curative surgical resection could improve their prognosis.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	1471-2482
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1186/s12893-017-0326-7