Histological Findings in the Trabecular Meshwork of a Patient with Atopic Glaucoma

Kase, Satoru; Chin, Shinki; Hamanaka, Teruhiko; Shinmei, Yasuhiro; Ohguchi, Takeshi; Kijima, Riki; Matsuda, Akira; Ishida, Susumu

Histological Findings in the Trabecular Meshwork of a Patient with Atopic Glaucoma

Kase, Satoru; Chin, Shinki; Hamanaka, Teruhiko et al.

The Open Ophthalmology Journal, 2017, 11, 103-106

Permalink : https://hdl.handle.net/2115/69977

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アクセス権	open access
URI	https://hdl.handle.net/2115/69977
タイトル	Histological Findings in the Trabecular Meshwork of a Patient with Atopic Glaucoma
著者	Kase, Satoru ; Chin, Shinki ; Hamanaka, Teruhiko ; Shinmei, Yasuhiro ; Ohguchi, Takeshi ; Kijima, Riki ; Matsuda, Akira ; Ishida, Susumu
e-Rad_Researcher 60374394 著者名 Kase, Satoru
e-Rad_Researcher 90236844 著者名 Chin, Shinki 著者別名 Chin, Shiki
著者名 Hamanaka, Teruhiko
e-Rad_Researcher 00374398 著者名 Shinmei, Yasuhiro
著者名 Ohguchi, Takeshi
著者名 Kijima, Riki
著者名 Matsuda, Akira
e-Rad_Researcher 10245558 著者名 Ishida, Susumu
言語	英語
キーワード	Atopic glaucoma
	Trabeculotomy
	Histopathology
	Intraocular pressure
	Postoperative fibrosis
	Trabecular meshwork
発行日	2017-05-29
出版者	Bentham Science Publishers
収録物名	The Open Ophthalmology Journal
巻(号)	11
ページ	103-106
記述	The author name "Shiki" is a typographical error for "Shinki".
抄録	Purpose: The aim of this study was to report a case of atopic dermatitis showing elevated intraocular pressure (IOP) beyond the baseline levels followed by a modified 360-degree suture trabeculotomy, and to analyze the histological findings in the trabecular meshwork. Methods: A 40-year-old male suffered from blurred vision in the right eye (OD). He had a medical history of severe atopic dermatitis and intraocular lens implantation OU due to atopic cataract. At the initial presentation, the visual acuity was 0.03, and IOP was 35 mmHg OD. Slit-lamp examination demonstrated corneal epithelial edema OD. Increased IOP was refractory to several topical medications. The patient underwent a modified 360-degree suture trabeculotomy. The visual field defect, however, deteriorated with persistently high IOP. The patient underwent trabeculectomy together with drainage implant surgery. In the outflow routes, although there seemed to be an opening of Schlemm's canal into the anterior chamber, there was no endothelium of the canal in the region of its opening. The fibrotic changes were conspicuous around Schlemm's canal. Conclusion: The histological results indicated that trabeculotomy might not be an appropriate treatment for patients with atopic glaucoma, possibly because of excessive repair to the newly created uveoscleral outflow in addition to the increased postoperative fibrosis in the trabecular meshwork and Schlemm's canal.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	1874-3641
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.2174/1874364101711010103