The Effect of Everolimus on Refractory Hypoglycemia in a Patient with Inoperable Metastatic Insulinoma Evaluated by Continuous Glucose Monitoring

Yanagiya, Shingo; Cho, Kyu Yong; Nakamura, Akinobu et al.

Internal medicine, 2018, 57(17), 2527-2531

Permalink : https://hdl.handle.net/2115/71863

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/71863
タイトル
The Effect of Everolimus on Refractory Hypoglycemia in a Patient with Inoperable Metastatic Insulinoma Evaluated by Continuous Glucose Monitoring
著者
Yanagiya, Shingo ; Cho, Kyu Yong ; Nakamura, Akinobu ; Nomoto, Hiroshi ; Kawamoto, Yasuyuki ; Kawakubo, Kazumichi ; Komatsu, Yoshito ; Mitsuhashi, Tomoko ; Miyoshi, Hideaki ; Atsumi, Tatsuya
著者名
Yanagiya, Shingo
著者名
Cho, Kyu Yong
e-Rad_Researcher
70552420
著者名
Nakamura, Akinobu
著者名
Nomoto, Hiroshi
著者名
Kawamoto, Yasuyuki
e-Rad_Researcher
80633578
著者名
Kawakubo, Kazumichi
e-Rad_Researcher
60333598
著者名
Komatsu, Yoshito
e-Rad_Researcher
60348208
著者名
Mitsuhashi, Tomoko
e-Rad_Researcher
30360902
著者名
Miyoshi, Hideaki
e-Rad_Researcher
20301905
著者名
Atsumi, Tatsuya
言語
英語
キーワード
everolimus
hypoglycemia
continuous glucose monitoring
発行日
2018-09-01
出版者
The Japanese Society of Internal Medicine
収録物名
Internal medicine
巻(号)
57(17)
ページ
2527-2531
抄録
An 84-year-old Japanese woman with metastatic insulinoma suffered from frequent hypoglycemic events. Continuous glucose monitoring (CGM) confirmed severe and frequent symptomatic/asymptomatic hypoglycemia. After the initiation of everolimus treatment, the hypoglycemic events were rapidly eliminated. CGM revealed that her blood glucose levels were maintained without hypoglycemia throughout the day. Furthermore, everolimus reduced the duration of time above the upper limit (>180 mg/dL) along with the standard deviation and mean amplitude of glycemic excursions. This case shows the potential effects of everolimus on hypoglycemia and glycemic control in a patient with inoperable metastatic insulinoma evaluated by CGM.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN
0918-2918
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.2169/internalmedicine.0126-17