Dietary intakes of fat soluble vitamins as predictors of mortality from heart failure in a large prospective cohort study

Eshak, Ehab S.; Iso, Hiroyasu; Yamagishi, Kazumasa; Cui, Renzhe; Tamakoshi, Akiko

Dietary intakes of fat soluble vitamins as predictors of mortality from heart failure in a large prospective cohort study

Eshak, Ehab S.; Iso, Hiroyasu; Yamagishi, Kazumasa et al.

Nutrition, 2018, 47, 50-55

Permalink : https://hdl.handle.net/2115/72728

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/72728
タイトル	Dietary intakes of fat soluble vitamins as predictors of mortality from heart failure in a large prospective cohort study
その他のタイトル	Fat soluble vitamins and heart failure death
著者	Eshak, Ehab S. ; Iso, Hiroyasu ; Yamagishi, Kazumasa ; Cui, Renzhe ; Tamakoshi, Akiko
著者名 Eshak, Ehab S.
e-Rad_Researcher 50223053 著者名 Iso, Hiroyasu
著者名 Yamagishi, Kazumasa
著者名 Cui, Renzhe
e-Rad_Researcher 90236737 著者名 Tamakoshi, Akiko
言語	英語
キーワード	Dietary vitamin A
	Dietary vitamin K
	Dietary vitamin E
	Dietary vitamin D
	Heart failure mortality
	Japanese
発行日	2018-03
出版者	Elsevier
収録物名	Nutrition
巻(号)	47
ページ	50-55
抄録	Objective: A few reports have investigated the association of dietary vitamin intakes with risk of heart failure in Asia. Therefore, we examined the relation of dietary intakes of fat-soluble vitamins A, K E, and D with mortality from heart failure in Japanese population. Research Methods and Procedures: A total of 23,099 men and 35,597 women aged 40-79 years participated in the Japan Collaborative Cohort Study and completed a food frequency questionnaire, from which dietary intakes of vitamin A, K, E and D were calculated. Cox proportional hazard model was used to estimate the sex-specific risk of heart failure mortality according to increasing quintiles of fat soluble vitamin intakes. Results: During median 19.3-year follow-up, there were 567 deaths from heart failure (395 men and 307 women). Dietary vitamin A intake showed no association with heart failure mortality in both genders; contrary, the reduced risk was observed in women but not in men with dietary intakes of vitamin K, E and D. The multivariable HRs (95% CI) in the highest versus the lowest intake quintiles among women were 0.63 (0.45, 0.87; P for trend=0.006) for vitamin K, 0.55 (0.36, 0.78; P for trend=0.006) for vitamin E and 0.66 (0.48, 0.93; P for trend= 0.01) for vitamin D. The association for each vitamin was slightly attenuated but remained statistically significant after mutual adjustment for other vitamins. Conclusions: High dietary intakes of fat soluble vitamins K, E and D were associated with reduced risk of heart failure mortality in Japanese women but not men.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	0899-9007
関連情報	PMID 29429535
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.nut.2017.09.009