Predictive factors for hyperglycaemic progression in patients with schizophrenia or bipolar disorder

Kusumi, Ichiro; Arai, Yuki; Okubo, Ryo et al.

BJPsych Open, 2018, 4(6), 454-460

Permalink : https://hdl.handle.net/2115/72975

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アクセス権
open access
URI
https://hdl.handle.net/2115/72975
タイトル
Predictive factors for hyperglycaemic progression in patients with schizophrenia or bipolar disorder
著者
Kusumi, Ichiro ; Arai, Yuki ; Okubo, Ryo ; Honda, Minoru ; Matsuda, Yasuhiro ; Matsuda, Yukihiko ; Tochigi, Akihiko ; Takekita, Yoshiteru ; Yamanaka, Hiroyoshi ; Uemura, Keiichi ; Ito, Koichi ; Tsuchiya, Kiyoshi ; Yamada, Jun ; Yoshimura, Bunta ; Mitsui, Nobuyuki ; Matsubara, Sigehiro ; Segawa, Takayuki ; Nishi, Nobuyuki ; Sugawara, Yasufumi ; Kako, Yuki ; Shinkawa, Ikuta ; Shinohara, Kaoru ; Konishi, Akiko ; Iga, Junichi ; Hashimoto, Naoki ; Inomata, Shinsaku ; Tsukamoto, Noriko ; Ito, Hiroto ; Ito, Yoichi M. ; Sato, Norihiro
e-Rad_Researcher
30250426
著者名
Kusumi, Ichiro
著者名
Arai, Yuki
著者名
Okubo, Ryo
著者名
Honda, Minoru
著者名
Matsuda, Yasuhiro
著者名
Matsuda, Yukihiko
著者名
Tochigi, Akihiko
著者名
Takekita, Yoshiteru
著者名
Yamanaka, Hiroyoshi
著者名
Uemura, Keiichi
著者名
Ito, Koichi
著者名
Tsuchiya, Kiyoshi
著者名
Yamada, Jun
著者名
Yoshimura, Bunta
著者名
Mitsui, Nobuyuki
著者名
Matsubara, Sigehiro
著者名
Segawa, Takayuki
著者名
Nishi, Nobuyuki
著者名
Sugawara, Yasufumi
e-Rad_Researcher
70374444
著者名
Kako, Yuki
著者名
Shinkawa, Ikuta
著者名
Shinohara, Kaoru
著者名
Konishi, Akiko
著者名
Iga, Junichi
著者名
Hashimoto, Naoki
著者名
Inomata, Shinsaku
著者名
Tsukamoto, Noriko
著者名
Ito, Hiroto
e-Rad_Researcher
10334236
著者名
Ito, Yoichi M.
著者名
Sato, Norihiro
言語
英語
キーワード
Schizophrenia
bipolar disorder
diabetes
monitoring
発行日
2018-11
出版者
Cambridge University Press
収録物名
BJPsych Open
巻(号)
4(6)
ページ
454-460
抄録
Background: Patients with schizophrenia or bipolar disorder have a high risk of developing type 2 diabetes. Aims: To identify predictive factors for hyperglycaemic progression in individuals with schizophrenia or bipolar disorder and to determine whether hyperglycaemic progression rates differ among antipsychotics in regular clinical practice. Method: We recruited 1166 patients who initially had normal or prediabetic glucose levels for a nationwide, multisite, l-year prospective cohort study to determine predictive factors for hyperglycaemic progression. We also examined whether hyperglycaemic progression varied among patients receiving monotherapy with the six most frequently used antipsychotics. Results: High baseline serum triglycerides and coexisting hypertension significantly predicted hyperglycaemic progression. The six most frequently used antipsychotics did not significantly differ in their associated hyperglycaemic progression rates over the 1-year observation period. Conclusions: Clinicians should carefully evaluate baseline serum triglycerides and coexisting hypertension and perform strict longitudinal monitoring irrespective of the antipsychotic used.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報
© The Royal College of Psychiatrists 2018
PISSN
2056-4724
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.1192/bjo.2018.56