Relation between total shock energy and mortality in patients with implantable cardioverter-defibrillator

Tenma, Taro; Yokoshiki, Hisashi; Mitsuyama, Hirofumi; Watanabe, Masaya; Mizukami, Kazuya; Kamada, Rui; Takahashi, Masayuki; Sasaki, Ryo; Maeno, Motoki; Okamoto, Kaori; Chiba, Yuki; Anzai, Toshihisa

Relation between total shock energy and mortality in patients with implantable cardioverter-defibrillator

Tenma, Taro; Yokoshiki, Hisashi; Mitsuyama, Hirofumi et al.

International journal of cardiology, 2018, 259, 94-99

Permalink : https://hdl.handle.net/2115/74003

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アクセス権	open access
URI	https://hdl.handle.net/2115/74003
タイトル	Relation between total shock energy and mortality in patients with implantable cardioverter-defibrillator
著者	Tenma, Taro ; Yokoshiki, Hisashi ; Mitsuyama, Hirofumi ; Watanabe, Masaya ; Mizukami, Kazuya ; Kamada, Rui ; Takahashi, Masayuki ; Sasaki, Ryo ; Maeno, Motoki ; Okamoto, Kaori ; Chiba, Yuki ; Anzai, Toshihisa
著者名 Tenma, Taro
e-Rad_Researcher 40360911 著者名 Yokoshiki, Hisashi
著者名 Mitsuyama, Hirofumi
著者名 Watanabe, Masaya
著者名 Mizukami, Kazuya
著者名 Kamada, Rui
著者名 Takahashi, Masayuki
著者名 Sasaki, Ryo
著者名 Maeno, Motoki
著者名 Okamoto, Kaori
著者名 Chiba, Yuki
著者名 Anzai, Toshihisa
言語	英語
キーワード	Total shock energy
	Implantable cardioverter-defibrillator
	Mortality
	Shock accumulation
	Low left ventricular ejection fraction
	Atrial fibrillation
発行日	2018-05-15
出版者	Elsevier
収録物名	International journal of cardiology
巻(号)	259
ページ	94-99
抄録	Background: Implantable Cardioverter-Defibrillator (ICD) shocks have been associated with mortality. However, no study has examined the relation between total shock energy and mortality. The aim of this study is to assess the association of total shock energy with mortality, and to determine the patients who are at risk of this association. Methods: Data from 316 consecutive patients who underwent initial ICD implantation in our hospital between 2000 and 2011 were retrospectively studied. We collected shock energy for 3 years from the ICD implantation, and determined the relation of shock energy on mortality after adjusting confounding factors. Results: Eighty-seven ICD recipients experienced shock(s) within 3 years from ICD implantation and 43 patients had died during the follow-up. The amount of shock energy was significantly associated with all-cause death [adjusted hazard ratio (HR) 1.26 (per 100 joule increase), p < 0.01] and tended to be associated with cardiac death (adjusted HR 1.30, p = 0.08). The survival rate of patients with high shock energy accumulation (>= 182 joule) was lower (p = 0.05), as compared to low shock energy accumulation (<182 joule), likewise to no shock. Besides, the relation between high shock energy accumulation and all-cause death was remarkable in the patients with low left ventricular ejection fraction (LVEF <= 40%) or atrial fibrillation (AF). Conclusions: Increase of shock energywas related tomortality in ICD recipients. This relation was evident in patients with low LVEF or AF.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	0167-5273
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.ijcard.2018.02.063