Mollaret Meningitis with a High Level of Cytokines in the Cerebrospinal Fluid Successfully Treated by Indomethacin

Kawabori, Masahito; Kurisu, Kota; Niiya, Yoshimasa et al.

Internal medicine, 2019, 58(8), 1163-1166

Permalink : https://hdl.handle.net/2115/74484

このアイテムのアクセス数:723件（2026-08-12 00:31 集計）

閲覧可能ファイル 

ファイル フォーマット サイズ 閲覧回数 説明
58_1676-18 pdf 132 KB 458

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権
open access
URI
https://hdl.handle.net/2115/74484
タイトル
Mollaret Meningitis with a High Level of Cytokines in the Cerebrospinal Fluid Successfully Treated by Indomethacin
著者
Kawabori, Masahito ; Kurisu, Kota ; Niiya, Yoshimasa ; Ohta, Yuzuru ; Mabuchi, Shoji ; Houkin, Kiyohiro
e-Rad_Researcher
50399870
著者名
Kawabori, Masahito
著者名
Kurisu, Kota
著者名
Niiya, Yoshimasa
著者名
Ohta, Yuzuru
著者名
Mabuchi, Shoji
e-Rad_Researcher
90229146
著者名
Houkin, Kiyohiro
言語
英語
キーワード
Mollaret meningitis
recurrent aseptic meningitis
fever
indomethacin
cytokines
発行日
2019-04-15
出版者
日本内科学会
The Japanese Society of Internal Medicine
収録物名
Internal medicine
巻(号)
58(8)
ページ
1163-1166
抄録
A rare case of Mollaret meningitis characterized by four recurrent episodes of aseptic meningitis during a three-year period is reported. The patient showed a high fever and severe headache accompanied by a high level of cerebrospinal fluid (CSF) cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha). The symptoms and high CSF cytokines were resolved immediately after introducing indomethacin treatment. Reactivation of the latent virus is considered to be the cause of this rare disease, and indomethacin is believed to inhibit the periodic abnormal generation of eicosanoid in the brain, resulting in a reduction in the fever and subsequent inflammation.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN
0918-2918
関連情報
PMID
30568139
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.2169/internalmedicine.1676-18