Clinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan

Ishiguro, Nobuhisa; Koseki, Naoko; Kaiho, Miki et al.

Journal of infection and chemotherapy, 2018, 24(6), 449-457

Permalink : https://hdl.handle.net/2115/74500

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アクセス権
open access
URI
https://hdl.handle.net/2115/74500
タイトル
Clinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan
著者
Ishiguro, Nobuhisa ; Koseki, Naoko ; Kaiho, Miki ; Ariga, Tadashi ; Kikuta, Hideaki ; Oba, Koji ; Togashi, Takehiro ; Morita, Keisuke ; Inagawa, Akira ; Okamura, Akiko ; Yamazaki, Shigeru ; Shida, Satoru ; Konno, Mutsuko ; Kawamura, Nobuaki ; Ishizaka, Akihito ; Takada, Kimihiko ; Tsubakihara, Keiji ; Nagano, Naoko ; Shibata, Mutsuo ; Furuyama, Hideto ; Matsuzono, Yoshihiro ; Koike, Akemi ; Murashita, Mari ; Hatae, Yoshio ; Arioka, Hideki ; Yamanaka, Tatsuru ; Watanabe, Toru ; Tabata, Yuuichi ; Kumita, Yoshihiro ; Hazama, Kyosuke ; Akutsu, Yasushi ; Aoyagi, Hayato ; Tobise, Chie ; Azuma, Katsuki ; Yasoshima, Kohichi ; Sawada, Yoko ; Uetsuji, Kazuyuki ; Tsuchida, Akira ; Tsuchiyama, Akira ; Yasuda, Kazue ; Odagawa, Yasuhisa ; Yoshioka, Mikio
e-Rad_Researcher
40168216
著者名
Ishiguro, Nobuhisa
著者名
Koseki, Naoko
著者名
Kaiho, Miki
e-Rad_Researcher
60322806
著者名
Ariga, Tadashi
著者名
Kikuta, Hideaki
e-Rad_Researcher
30422926
著者名
Oba, Koji
著者名
Togashi, Takehiro
著者名
Morita, Keisuke
著者名
Inagawa, Akira
著者名
Okamura, Akiko
著者名
Yamazaki, Shigeru
著者名
Shida, Satoru
著者名
Konno, Mutsuko
e-Rad_Researcher
90301879
著者名
Kawamura, Nobuaki
著者名
Ishizaka, Akihito
著者名
Takada, Kimihiko
著者名
Tsubakihara, Keiji
著者名
Nagano, Naoko
著者名
Shibata, Mutsuo
著者名
Furuyama, Hideto
著者名
Matsuzono, Yoshihiro
著者名
Koike, Akemi
著者名
Murashita, Mari
著者名
Hatae, Yoshio
著者名
Arioka, Hideki
著者名
Yamanaka, Tatsuru
著者名
Watanabe, Toru
著者名
Tabata, Yuuichi
著者名
Kumita, Yoshihiro
著者名
Hazama, Kyosuke
著者名
Akutsu, Yasushi
著者名
Aoyagi, Hayato
著者名
Tobise, Chie
著者名
Azuma, Katsuki
著者名
Yasoshima, Kohichi
著者名
Sawada, Yoko
著者名
Uetsuji, Kazuyuki
著者名
Tsuchida, Akira
著者名
Tsuchiyama, Akira
著者名
Yasuda, Kazue
著者名
Odagawa, Yasuhisa
著者名
Yoshioka, Mikio
言語
英語
キーワード
Oseltamivir
Zanamivir
Laninamivir
Peramivir
Influenza A
Influenza B
発行日
2018-06
出版者
Elsevier
収録物名
Journal of infection and chemotherapy
巻(号)
24(6)
ページ
449-457
抄録
The clinical effectiveness of four neuraminidase inhibitors (NAIs) (oseltamivir, zanamivir, laninamivir, and peramivir) for children aged 0 months to 18 years with influenza A and B were investigated in the 2014-2015 to 2016-2017 influenza seasons in Japan. A total of 1207 patients (747 with influenza A and 460 with influenza B) were enrolled. The Cox proportional-hazards model using all of the patients showed that the duration of fever after administration of the first dose of the NAI was shorter in older patients (hazard ratio = 1.06 per 1 year of age, p < 0.001) and that the duration of fever after administration of the first dose of the NAI was shorter in patients with influenza A infection than in patients with influenza B infection (hazard ratio = 2.21, p < 0.001). A logistic regression model showed that the number of biphasic fever episodes was 2.99-times greater for influenza B-infected patients than for influenza A-infected patients (p < 0.001). The number of biphasic fever episodes in influenza A-or B-infected patients aged 0-4 years was 2.89-times greater than that in patients aged 10-18 years (p = 0.010), and the number of episodes in influenza A-or B-infected patients aged 5-9 years was 2.13times greater than that in patients aged 10-18 years (p = 0.012).
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報
© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN
1341-321X
関連情報
PMID
29487035
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1016/j.jiac.2018.01.013