Comparison of the University of Pittsburgh staging system and the eighth edition of the American Joint Committee on Cancer TNM classification for the prognostic evaluation of external auditory canal cancer

Morita, Shinya; Mizumachi, Takatsugu; Nakamaru, Yuji; Sakashita, Tomohiro; Kano, Satoshi; Hoshino, Kimiko; Fukuda, Atsushi; Fujiwara, Keishi; Homma, Akihiro

Comparison of the University of Pittsburgh staging system and the eighth edition of the American Joint Committee on Cancer TNM classification for the prognostic evaluation of external auditory canal cancer

Morita, Shinya; Mizumachi, Takatsugu; Nakamaru, Yuji et al.

International journal of clinical oncology, 2018, 23(6), 1029-1037

Permalink : https://hdl.handle.net/2115/74899

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アクセス権	open access
URI	https://hdl.handle.net/2115/74899
タイトル	Comparison of the University of Pittsburgh staging system and the eighth edition of the American Joint Committee on Cancer TNM classification for the prognostic evaluation of external auditory canal cancer
著者	Morita, Shinya ; Mizumachi, Takatsugu ; Nakamaru, Yuji ; Sakashita, Tomohiro ; Kano, Satoshi ; Hoshino, Kimiko ; Fukuda, Atsushi ; Fujiwara, Keishi ; Homma, Akihiro
著者名 Morita, Shinya
e-Rad_Researcher 00507577 著者名 Mizumachi, Takatsugu
e-Rad_Researcher 20344509 著者名 Nakamaru, Yuji
e-Rad_Researcher 30455654 著者名 Sakashita, Tomohiro
e-Rad_Researcher 00374421 著者名 Kano, Satoshi
著者名 Hoshino, Kimiko
著者名 Fukuda, Atsushi
著者名 Fujiwara, Keishi
e-Rad_Researcher 30312359 著者名 Homma, Akihiro
言語	英語
キーワード	External auditory canal cancer
	The University of Pittsburgh staging system
	Eighth edition
	AJCC
	TNM classification
発行日	2018-12
出版者	Springer
収録物名	International journal of clinical oncology
巻(号)	23(6)
ページ	1029-1037
抄録	Background: The purpose was to compare survival differences between patients with external auditory canal (EAC) cancer treated according to the University of Pittsburgh modified TNM staging system and those treated in accordance with the 8th edition of the American Joint Committee on Cancer (AJCC) staging manual on the TNM staging system for cutaneous cancers of the head and neck. Methods: We performed a retrospective, single-institution review of 60 patients with EAC cancer treated with curative intent between September 2002 and March 2018. Survival outcomes were measured on the basis of the two staging systems. Results: The C-index values for the overall survival (OS) rate revealed that the University of Pittsburgh staging system had higher prognostic accuracy than the 8th edition of the AJCC staging system. Univariable and multivariable analysis showed that T classification according to the University of Pittsburgh staging system was an independent predictor of the OS rate (hazard ratio 5.25; 95% confidence interval 1.38-24.9; P = 0.015). Meanwhile, the AJCC staging system could not differentiate T2 from T3-4 cancers. Conclusion: The University of Pittsburgh staging system for patients with EAC cancer is a valuable tool for use in clinical decision-making and predicting survival outcome.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is a post-peer-review, pre-copyedit version of an article published in International Journal of Clinical Oncology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10147-018-1314-3
PISSN	1341-9625
関連情報	PMID 29974295
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s10147-018-1314-3