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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/75071
タイトル	Further applications of classical amide coupling reagents: Microwave-assisted esterification on solid phase
著者	Takayama, Risa ; Hayakawa, Shun ; Hinou, Hiroshi ; Albericio, Fernando ; Garcia-Martin, Fayna
著者名 Takayama, Risa
著者名 Hayakawa, Shun
e-Rad_Researcher 70333333 著者名 Hinou, Hiroshi
著者名 Albericio, Fernando
e-Rad_Researcher 30537080 著者名 Garcia-Martin, Fayna
言語	英語
キーワード	solid-phase synthesis
	esterification
	microwave irradiation
	depsipeptide
発行日	2018-08
出版者	John Wiley & Sons
収録物名	Journal of peptide science
巻(号)	24(8-9)
ページ	UNSP e3111
抄録	Ester linkage (s) is a key chemical connector in organic chemistry, including natural products, peptides, and synthetic polymers. We herein describe a straightforward method for the efficient formation of ester linkage (s) on solid-phase. This method simply involves the use of amide coupling reagents under microwave irradiation. The robustness of this method relies on the use of classical solid-phase coupling reagents, heating by microwave irradiation, and a short time period, which results in high yields and the minimization of racemization.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is the peer reviewed version of the following article: Journal of Peptide Science Volume24, Issue8-9, August-September 2018, e3111, which has been published in final form at https://doi.org/10.1002/psc.3111 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
PISSN	1075-2617
関連情報	PMID 30009478
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1002/psc.3111

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