Identification of group A rotaviruses from Zambian fruit bats provides evidence for long-distance dispersal events in Africa

Sasaki, Michihito; Kajihara, Masahiro; Changula, Katendi; Kajihara, Akina; Ogawa, Hirohito; Hang'ombe, Bernard M.; Mweene, Aaron S.; Simuunza, Martin; Yoshida, Reiko; Carr, Michael; Orba, Yasuko; Takada, Ayato; Sawa, Hirofumi

Identification of group A rotaviruses from Zambian fruit bats provides evidence for long-distance dispersal events in Africa

Sasaki, Michihito; Kajihara, Masahiro; Changula, Katendi et al.

Infection, genetics and evolution, 2018, 63, 104-109

Permalink : https://hdl.handle.net/2115/75328

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アクセス権	open access
URI	https://hdl.handle.net/2115/75328
タイトル	Identification of group A rotaviruses from Zambian fruit bats provides evidence for long-distance dispersal events in Africa
著者	Sasaki, Michihito ; Kajihara, Masahiro ; Changula, Katendi ; Kajihara, Akina ; Ogawa, Hirohito ; Hang'ombe, Bernard M. ; Mweene, Aaron S. ; Simuunza, Martin ; Yoshida, Reiko ; Carr, Michael ; Orba, Yasuko ; Takada, Ayato ; Sawa, Hirofumi
e-Rad_Researcher 70609403 著者名 Sasaki, Michihito
e-Rad_Researcher 70711894 著者名 Kajihara, Masahiro
著者名 Changula, Katendi
著者名 Kajihara, Akina 著者別名 Mori, Akina
e-Rad_Researcher 80455237 著者名 Ogawa, Hirohito
著者名 Hang'ombe, Bernard M.
著者名 Mweene, Aaron S.
著者名 Simuunza, Martin
e-Rad_Researcher 80435966 著者名 Yoshida, Reiko
e-Rad_Researcher 70769588 著者名 Carr, Michael
e-Rad_Researcher 60507169 著者名 Orba, Yasuko
e-Rad_Researcher 10292062 著者名 Takada, Ayato
e-Rad_Researcher 30292006 著者名 Sawa, Hirofumi
言語	英語
キーワード	Rotavirus
	African fruit bats
	Long-distance dispersal
	Interspecies transmission
	Phylogenetic analysis
	Novel RVA genotypes
発行日	2018-09
出版者	Elsevier
収録物名	Infection, genetics and evolution
巻(号)	63
ページ	104-109
抄録	Group A rotavirus (RVA) is a major cause of diarrhea in children worldwide. Although RVA infects many animals, little is known about RVA in bats. The present study investigated the genetic diversity of RVA in Zambian bats. We identified RVA from two straw-colored fruit bats (Eidolon helvum) and an Egyptian fruit bat (Rousettus aegyptiacus), and analyzed the genome sequences of these strains. Genome segments of the RVA strains from Zambian E. helvum showed 97%–99% nucleotide sequence identity with those of other RVA strains from E. helvum in Cameroon, which is 2800 km from the sampling locations. These findings suggest that migratory straw-colored fruit bat species, distributed across sub-Saharan Africa, have the potential to disseminate RVA across long distances. By contrast, the RVA strain from Zambian R. aegyptiacus carried highly divergent NSP2 and NSP4 genes, leading us to propose novel genotypes N21 and E27, respectively. Notably, this RVA strain also shared the same genotype for VP6 and NSP3 with the RVA strains from Zambian E. helvum, suggesting interspecies transmission and genetic reassortment may have occurred between these two bat species in the past. Our study has important implications for RVA dispersal in bat populations, and expands our knowledge of the ecology, diversity and evolutionary relationships of RVA.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	1567-1348
EISSN	1567-7257
関連情報	PMID 29792990
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.meegid.2018.05.016