Relation of Systolic Blood Pressure on the Following Day with Post-Discharge Mortality in Hospitalized Heart Failure Patients with Preserved Ejection Fraction A Report from the JASPER Registry

Sato, Yu; Yoshihisa, Akiomi; Oikawa, Masayoshi; Nagai, Toshiyuki; Yoshikawa, Tsutomu; Saito, Yoshihiko; Yamamoto, Kazuhiro; Takeishi, Yasuchika; Anzai, Toshihisa

Relation of Systolic Blood Pressure on the Following Day with Post-Discharge Mortality in Hospitalized Heart Failure Patients with Preserved Ejection Fraction A Report from the JASPER Registry

Sato, Yu; Yoshihisa, Akiomi; Oikawa, Masayoshi et al.

International heart journal, 2019, 60(4), 876-885

Permalink : https://hdl.handle.net/2115/75342

このアイテムのアクセス数:615件（2026-10-17 07:00 集計）

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https://doi.org/10.1536/ihj.18-699			22

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アクセス権	open access
URI	https://hdl.handle.net/2115/75342
タイトル	Relation of Systolic Blood Pressure on the Following Day with Post-Discharge Mortality in Hospitalized Heart Failure Patients with Preserved Ejection Fraction A Report from the JASPER Registry
著者	Sato, Yu ; Yoshihisa, Akiomi ; Oikawa, Masayoshi ; Nagai, Toshiyuki ; Yoshikawa, Tsutomu ; Saito, Yoshihiko ; Yamamoto, Kazuhiro ; Takeishi, Yasuchika ; Anzai, Toshihisa
著者名 Sato, Yu
e-Rad_Researcher 40448642 著者名 Yoshihisa, Akiomi
e-Rad_Researcher 30457775 著者名 Oikawa, Masayoshi
e-Rad_Researcher 00528218 著者名 Nagai, Toshiyuki
著者名 Yoshikawa, Tsutomu
e-Rad_Researcher 30250260 著者名 Saito, Yoshihiko
e-Rad_Researcher 90303966 著者名 Yamamoto, Kazuhiro
e-Rad_Researcher 40272067 著者名 Takeishi, Yasuchika
e-Rad_Researcher 60232089 著者名 Anzai, Toshihisa
言語	英語
キーワード	Prognosis
発行日	2019-07
出版者	International Heart Journal Association
収録物名	International heart journal
巻(号)	60(4)
ページ	876-885
抄録	The clinical scenario, which is based on systolic blood pressure (SBP) upon admission, is useful for classifying and determining initial treatment for acute heart failure (HF). However, the prognostic significance of SBP following the initial treatment is unclear. The Japanese Heart Failure Syndrome with Preserved Ejection Fraction (JASPER) registry is a nationwide, observational, and prospective registration of consecutive Japanese patients hospitalized with HF with preserved ejection fraction (HFpEF) and left ventricular ejection fraction >= 50%. We divided 525 patients into three groups based on their SBP on the day following hospitalization: high (SBP > 140 mmHg, n = 72, 13.7%); normal (100 <= SBP <= 140 mmHg, n = 379, 72.2%); and low (SBP < 100 mmHg, n = 74, 14.1%) groups. This analysis had two primary endpoints: (1) all-cause death and (2) all-cause death or rehospitalization for HF. In the Kaplan-Meier analysis, both of the endpoints were the highest in the low group (Log-Rank < 0.05, respectively). Compared to the normal and high groups, the low group demonstrated a higher prevalence of atrial fibrillation (67.1%, 63.9%, and 47.8%, P = 0.026) and the lowest left ventricular outflow tract velocity time integral determined by echocardiography (16.4 cm, 19.4 cm, and 23.3 cm, P = 0.001). In the multivariable Cox proportional hazard analysis, low SBP on the day following hospitalization was an independent predictor of all-cause death (hazard ratio 1.868, 95% confidence interval 1.024-3.407, P = 0.042) and the composite endpoint (hazard ratio 1.660, 95% confidence interval 1.103-2.500, P = 0.015). Classification based on SBP on the day following initial treatment predicts post-discharge prognosis in hospitalized patients with HFpEF.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
PISSN	1349-2365
関連情報	PMID 31257340
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1536/ihj.18-699