open access

https://hdl.handle.net/2115/76335

Seroprevalence of filovirus infection of Rousettus aegyptiacus bats in Zambia

Filovirus surveillance of bats in Zambia

英語

Marburgvirus

2018-12-15

Oxford University Press

Journal of Infectious Diseases

218(suppl 5)

S312-S317

Bats are suspected to play important roles in the ecology of filoviruses, including ebolaviruses and marburgviruses. A cave-dwelling fruit bat, Rousettus aegyptiacus, has been shown to be a reservoir of marburgviruses. Using an enzyme-linked immunosorbent assay with the viral glycoprotein antigen, we detected immunoglobulin G antibodies specific to multiple filoviruses in 158 of 290 serum samples of R aegyptiacus bats captured in Zambia during the years 2014-2017. In particular, 43.8% of the bats were seropositive to marburgvirus, supporting the notion that this bat species continuously maintains marburgviruses as a reservoir. Of note, distinct peaks of seropositive rates were repeatedly observed at the beginning of rainy seasons, suggesting seasonality of the presence of newly infected individuals in this bat population. These data highlight the need for continued monitoring of filovirus infection in this bat species even in countries where filovirus diseases have not been reported.

学術雑誌論文

Accepted Manuscript

This is a pre-copyedited, author-produced version of an article accepted for publication in The Journal of Infectious Diseases following peer review. The version of record Volume 218 Issue suppl_5, S312–S317, 2018 is available online at: https://doi.org/10.1093/infdis/jiy266.

0022-1899

1537-6613

AA0070010X