Associations between cognitive impairment and quality of life in euthymic bipolar patients

Toyoshima, Kuniyoshi; Kako, Yuki; Toyomaki, Atsuhito; Shimizu, Yusuke; Tanaka, Teruaki; Nakagawa, Shin; Inoue, Takeshi; Martinez-Aran, Anabel; Vieta, Eduard; Kusumi, Ichiro

Associations between cognitive impairment and quality of life in euthymic bipolar patients

Toyoshima, Kuniyoshi; Kako, Yuki; Toyomaki, Atsuhito et al.

Psychiatry research, 2019, 271, 510-515

Permalink : https://hdl.handle.net/2115/76442

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/76442
タイトル	Associations between cognitive impairment and quality of life in euthymic bipolar patients
著者	Toyoshima, Kuniyoshi ; Kako, Yuki ; Toyomaki, Atsuhito ; Shimizu, Yusuke ; Tanaka, Teruaki ; Nakagawa, Shin ; Inoue, Takeshi ; Martinez-Aran, Anabel ; Vieta, Eduard ; Kusumi, Ichiro
著者名 Toyoshima, Kuniyoshi
e-Rad_Researcher 70374444 著者名 Kako, Yuki
e-Rad_Researcher 70515494 著者名 Toyomaki, Atsuhito
著者名 Shimizu, Yusuke
著者名 Tanaka, Teruaki
e-Rad_Researcher 60360905 著者名 Nakagawa, Shin
e-Rad_Researcher 70250438 著者名 Inoue, Takeshi
著者名 Martinez-Aran, Anabel
著者名 Vieta, Eduard
e-Rad_Researcher 30250426 著者名 Kusumi, Ichiro
言語	英語
キーワード	Bipolar disorder
	Cognitive complaints
	Cognitive function
	Neuropsychological assessment
	COBRA
	SF-36v2
	SDS
発行日	2019-01
出版者	Elsevier
収録物名	Psychiatry research
巻(号)	271
ページ	510-515
抄録	During the euthymic state in bipolar disorder, cognitive functions often remain affected. Specifically, subjective and objective cognitive impairment might distinctly affect patients' quality of life (QoL); however, this question had not been examined previously in Japanese patients. Therefore, the current study investigated the associations between cognitive complaints, QoL, and objective cognitive functions. Forty patients in remission were recruited from the Hokkaido University Hospital, Sapporo, Japan and assessed with the translated version of the cognitive complaints in bipolar disorder rating assessment (COBRA), medical outcomes study 36-item short-form health survey version 2 (SF-36v2), and Sheehan disability scale (SDS). The Japanese adult reading scale, Wisconsin card sorting test, word fluency, continuous performance test, trail making test (TMT), auditory verbal learning, and Stroop test evaluated objective cognitive functions. Significant correlations were observed between the COBRA, SF-36v2, and SDS results, as well as the TMT scores. Overall, euthymic patients were aware of their cognitive dysfunction, which could be understood in relation to the decrease in satisfaction in their daily life. Therefore, even mild cognitive impairments can have ramifications for patients in the euthymic state of bipolar disorder.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	©2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	0165-1781
EISSN	1872-7123
関連情報	PMID 30551083
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.psychres.2018.11.061