Interaction Among Influenza Viruses A/H1N1, A/H3N2, and B in Japan

Suzuki, Ayako; Mizumoto, Kenji; Akhmetzhanov, Andrei R.; Nishiura, Hiroshi

Interaction Among Influenza Viruses A/H1N1, A/H3N2, and B in Japan

Suzuki, Ayako; Mizumoto, Kenji; Akhmetzhanov, Andrei R. et al.

International journal of environmental research and public health, 2019, 16(21), 4179

Permalink : https://hdl.handle.net/2115/76505

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ファイル	フォーマット	サイズ	閲覧回数	説明
https://doi.org/10.3390/ijerph16214179			17

論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/76505
タイトル	Interaction Among Influenza Viruses A/H1N1, A/H3N2, and B in Japan
著者	Suzuki, Ayako ; Mizumoto, Kenji ; Akhmetzhanov, Andrei R. ; Nishiura, Hiroshi
e-Rad_Researcher 90849986 著者名 Suzuki, Ayako
e-Rad_Researcher 90730218 著者名 Mizumoto, Kenji
著者名 Akhmetzhanov, Andrei R.
e-Rad_Researcher 70432987 著者名 Nishiura, Hiroshi
言語	英語
キーワード	influenza
	viral interference
	epidemics
	statistical model
	epidemiology
発行日	2019-11-01
出版者	MDPI
収録物名	International journal of environmental research and public health
巻(号)	16(21)
ページ	4179
抄録	Seasonal influenza epidemics occur each winter season in temperate zones, involving up to 650,000 deaths each year globally. A published study demonstrated that the circulation of one influenza virus type during early influenza season in the United States interferes with the activity of other influenza virus types. However, this finding has yet to be validated in other settings. In the present work, we investigated the interaction among seasonal influenza viruses (A/H1N1, A/H3N2 and B) in Japan. Sentinel and virus surveillance data were used to estimate the type-specific incidence from 2010 to 2019, and statistical correlations among the type-specific incidence were investigated. We identified significant negative correlations between incidence of the dominant virus and the complementary incidence. When correlation was identified during the course of an epidemic, a linear regression model accurately predicted the epidemic size of a particular virus type before the epidemic peak. The peak of influenza type B took place later in the season than that of influenza A, although the epidemic peaks of influenza A/H1N1 and A/H3N2 nearly coincided. Given the interaction among different influenza viruses, underlying mechanisms including age and spatial dependence should be explored in future.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	1661-7827
EISSN	1660-4601
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3390/ijerph16214179