Constant current stimulation may improve apraxia of eyelid opening induced by deep brain stimulation

Eguchi, Katsuki; Yabe, Ichiro; Shirai, Shinichi; Iwata, Ikuko; Matsushima, Masaaki; Yamazaki, Kazuyoshi; Hamauchi, Shuji; Sasamori, Toru; Seki, Toshitaka; Houkin, Kiyohiro; Sasaki, Hidenao

Constant current stimulation may improve apraxia of eyelid opening induced by deep brain stimulation

Eguchi, Katsuki; Yabe, Ichiro; Shirai, Shinichi et al.

Interdisciplinary Neurosurgery-advanced Techniques And Case Management, 2020, 19, UNSP 100565

Permalink : https://hdl.handle.net/2115/76730

このアイテムのアクセス数:697件（2026-08-17 18:06 集計）

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https://doi.org/10.1016/j.inat.2019.100565			10

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アクセス権	open access
URI	https://hdl.handle.net/2115/76730
タイトル	Constant current stimulation may improve apraxia of eyelid opening induced by deep brain stimulation
著者	Eguchi, Katsuki ; Yabe, Ichiro ; Shirai, Shinichi ; Iwata, Ikuko ; Matsushima, Masaaki ; Yamazaki, Kazuyoshi ; Hamauchi, Shuji ; Sasamori, Toru ; Seki, Toshitaka ; Houkin, Kiyohiro ; Sasaki, Hidenao
著者名 Eguchi, Katsuki
e-Rad_Researcher 60372273 著者名 Yabe, Ichiro
著者名 Shirai, Shinichi
著者名 Iwata, Ikuko
著者名 Matsushima, Masaaki
著者名 Yamazaki, Kazuyoshi
著者名 Hamauchi, Shuji
著者名 Sasamori, Toru
著者名 Seki, Toshitaka
e-Rad_Researcher 90229146 著者名 Houkin, Kiyohiro
e-Rad_Researcher 80281806 著者名 Sasaki, Hidenao
言語	英語
キーワード	Apraxia of eyelid opening
	Constant current stimulation
	Constant voltage stimulation
	Deep brain stimulation
	Parkinson's disease
	Subthalamic nucleus
発行日	2020-03
出版者	Elsevier
収録物名	Interdisciplinary Neurosurgery-advanced Techniques And Case Management
巻(号)	19
ページ	UNSP 100565
抄録	Background: Apraxia of eyelid opening (AEO) is a common side effect of subthalamic nucleus deep brain stimulation (STN-DBS) and difficult to treat. We report the case of a patient with Parkinson's disease (PD) whose DBS-induced AEO was alleviated after adjustment from constant-voltage (CV) to constant-current (CC) stimulation. Case description: A female patient with PD underwent bilateral STN-DBS surgery 12 years after onset. Three months after the start of stimulation, she developed bilateral AEO though her motor symptoms improved. Her AEO severity deteriorated in line with an increase in stimulation-voltage. Three years after surgery, we replaced the implantable pulse generators (IPGs) because of low voltage. We changed the stimulation programs from CV stimulation to CC stimulation as only CC stimulation was available on the new IPG model. Her AEO was significantly improved after the stimulation programs were changed from CV to CC stimulation, even though the stimulation intensity did not change markedly. Her motor symptoms did not change. We evaluated the association between AEO severity and stimulation contact point and found that stimulation at the lowest contact on the left side strongly induced AEO. Conclusion: Shifting from CV stimulation to CC stimulation may improve DBS-induced AEO. The exact mechanism underlying this improvement is unknown and further studies are needed to confirm the efficacy of CC stimulation for AEO.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN	2214-7519
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1016/j.inat.2019.100565