Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction

Tsuchihashi-Makaya, Miyuki; Hamaguchi, Sanae; Kinugawa, Shintaro et al.

Circulation Journal, 2009, 73(10), 1893-1900

Permalink : https://hdl.handle.net/2115/76966

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/76966
タイトル
Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction
著者
Tsuchihashi-Makaya, Miyuki ; Hamaguchi, Sanae ; Kinugawa, Shintaro ; Yokota, Takashi ; Goto, Daisuke ; Yokoshiki, Hisashi ; Kato, Norihiro ; Takeshita, Akira ; Tsutsui, Hiroyuki ; for the JCARE-CARD Investigators
著者名
Tsuchihashi-Makaya, Miyuki
著者名
Hamaguchi, Sanae
e-Rad_Researcher
60399871
著者名
Kinugawa, Shintaro
e-Rad_Researcher
90374321
著者名
Yokota, Takashi
著者名
Goto, Daisuke
e-Rad_Researcher
40360911
著者名
Yokoshiki, Hisashi
著者名
Kato, Norihiro
著者名
Takeshita, Akira
e-Rad_Researcher
70264017
著者名
Tsutsui, Hiroyuki
著者名
for the JCARE-CARD Investigators
言語
英語
キーワード
Ejection fraction
Heart failure
Mortality
Outcome
Rehospitalization
発行日
2009
収録物名
Circulation Journal
巻(号)
73(10)
ページ
1893-1900
抄録
Background: Heart failure (HF) with preserved ejection fraction (EF) is common. We compared the characteristics, treatments, and outcomes in HF patients with reduced vs preserved EF by using the national registry database in Japan. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) is a prospective observational study in a broad sample of patients hospitalized with worsening HF. The study enrolled 2,675 patients from 164 hospitals with an average of 2.4 years of follow-up. Patients with preserved EF (EF ?50% by echocardiography; n=429) were more likely to be older, female, have hypertension and atrial fibrillation, and less likely to have ischemic etiology compared with those with reduced EF (EF <40%; n=985). Unadjusted risk of in-hospital mortality (6.5% vs 3.9%; P=0.03) and post-discharge mortality (22.7% vs 17.8%; P=0.058) was slightly higher in patients with preserved EF, which, however, were not different after multivariable adjustment. Patients with preserved EF had similar rehospitalization rates (36.2% vs 33.4%; P=0.515) compared with patients with reduced EF. Conclusions: HF patients with preserved EF had a similar mortality risk and equally high rates of rehospitalization as those with reduced EF. Effective management strategies are critically needed to be established for this type of HF. (Circ J 2009; 73: 1893-1900)
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN
1346-9843
EISSN
1347-4820
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.1253/circj.CJ-09-0254