Body Mass Index Is an Independent Predictor of Long-Term Outcomes in Patients Hospitalized With Heart Failure in Japan

Hamaguchi, Sanae; Tsuchihashi-Makaya, Miyuki; Kinugawa, Shintaro; Goto, Daisuke; Yokota, Takashi; Goto, Kazutomo; Yamada, Satoshi; Yokoshiki, Hisashi; Takeshita, Akira; Tsutsui, Hiroyuki; for the JCARE-CARD Investigators

Body Mass Index Is an Independent Predictor of Long-Term Outcomes in Patients Hospitalized With Heart Failure in Japan

Hamaguchi, Sanae; Tsuchihashi-Makaya, Miyuki; Kinugawa, Shintaro et al.

Circulation Journal, 2010, 74(12), 2605-2611

Permalink : https://hdl.handle.net/2115/76970

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アクセス権	open access
URI	https://hdl.handle.net/2115/76970
タイトル	Body Mass Index Is an Independent Predictor of Long-Term Outcomes in Patients Hospitalized With Heart Failure in Japan
著者	Hamaguchi, Sanae ; Tsuchihashi-Makaya, Miyuki ; Kinugawa, Shintaro ; Goto, Daisuke ; Yokota, Takashi ; Goto, Kazutomo ; Yamada, Satoshi ; Yokoshiki, Hisashi ; Takeshita, Akira ; Tsutsui, Hiroyuki ; for the JCARE-CARD Investigators
著者名 Hamaguchi, Sanae
著者名 Tsuchihashi-Makaya, Miyuki
e-Rad_Researcher 60399871 著者名 Kinugawa, Shintaro
著者名 Goto, Daisuke
e-Rad_Researcher 90374321 著者名 Yokota, Takashi
著者名 Goto, Kazutomo
e-Rad_Researcher 80374320 著者名 Yamada, Satoshi
e-Rad_Researcher 40360911 著者名 Yokoshiki, Hisashi
著者名 Takeshita, Akira
e-Rad_Researcher 70264017 著者名 Tsutsui, Hiroyuki
著者名 for the JCARE-CARD Investigators
言語	英語
キーワード	Body mass index
	Heart failure
	Mortality
	Obesity
	Prognosis
発行日	2010
出版者	The Japanese Circulation Society
出版者	社団法人日本循環器学会
収録物名	Circulation Journal
巻(号)	74(12)
ページ	2605-2611
抄録	Background: Obesity is a risk factor for cardiovascular disease (CVD) and is also associated with an increased risk of death in subjects without CVD. However, in heart failure (HF), elevated body mass index (BMI) has been shown to be associated with better prognosis, but it is unknown whether this is the case in unselected HF patients encountered in routine clinical practice in Japan. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) studied prospectively the characteristics and treatments in a broad sample of patients hospitalized with worsening HF and the outcomes were followed for 2.1 years. Study cohort (n=2,488) was classified into 3 groups according to baseline BMI: <20.3kg/m2 (n=829), 20.3-23.49kg/m2 (n=832), and ≥23.5kg/m2 (n=827). The mean BMI was 22.3±4.1kg/m2. Patients with higher BMI had lower rates of all-cause death, cardiac death, and rehospitalization because of worsening HF. After multivariable adjustment, the risk for all-cause death and cardiac death significantly increased with decreased BMI levels compared with patients with BMI ≥23.5kg/m2. However, BMI levels were not associated with rehospitalization for worsening HF. Conclusions: Lower BMI was independently associated with increased long-term all-cause, as well as cardiac, mortality in patients with HF encountered in routine clinical practice in Japan. (Circ J 2010; 74: 2605-2611)
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN	1346-9843
EISSN	1347-4820
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1253/circj.CJ-10-0599