Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure

Hamaguchi, Sanae; Kinugawa, Shintaro; Goto, Daisuke; Tsuchihashi-Makaya, Miyuki; Yokota, Takashi; Yamada, Satoshi; Yokoshiki, Hisashi; Takeshita, Akira; Tsutsui, Hiroyuki; JCARE-CARD Investigators

Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure

Hamaguchi, Sanae; Kinugawa, Shintaro; Goto, Daisuke et al.

Circulation Journal, 2011, 75(10), 2403-2410

Permalink : https://hdl.handle.net/2115/76971

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アクセス権	open access
URI	https://hdl.handle.net/2115/76971
タイトル	Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure
著者	Hamaguchi, Sanae ; Kinugawa, Shintaro ; Goto, Daisuke ; Tsuchihashi-Makaya, Miyuki ; Yokota, Takashi ; Yamada, Satoshi ; Yokoshiki, Hisashi ; Takeshita, Akira ; Tsutsui, Hiroyuki ; JCARE-CARD Investigators
著者名 Hamaguchi, Sanae
e-Rad_Researcher 60399871 著者名 Kinugawa, Shintaro
著者名 Goto, Daisuke
著者名 Tsuchihashi-Makaya, Miyuki
e-Rad_Researcher 90374321 著者名 Yokota, Takashi
著者名 Yamada, Satoshi
e-Rad_Researcher 40360911 著者名 Yokoshiki, Hisashi
著者名 Takeshita, Akira
e-Rad_Researcher 70264017 著者名 Tsutsui, Hiroyuki
著者名 JCARE-CARD Investigators
言語	英語
キーワード	Elderly
	Heart failure
	Mortality
	Outcomes
	Prognosis
発行日	2011
出版者	The Japanese Circulation Society
出版者	社団法人日本循環器学会
収録物名	Circulation Journal
巻(号)	75(10)
ページ	2403-2410
抄録	Background: Aging is associated with adverse outcomes in patients with cardiac diseases. Whether elderly patients hospitalized with heart failure (HF) had increased risks for mortality and rehospitalization compared with younger patients during the long-term follow-up was examined. The predictors of these adverse outcomes were also identified. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) studied prospectively the characteristics and treatments in a broad sample of 2,675 patients hospitalized with worsening HF and the outcomes were followed up. The majority of elderly patients were female, had lower body mass index (BMI), a higher rate of ischemic, valvular, and hypertensive heart disease as etiologies of HF, a lower estimated glomerular filtration rate (eGFR), lower hemoglobin, and higher left ventricular ejection fraction values. Even after adjustment for covariates, the elderly patients were associated with higher risks of adverse outcomes. The predictors for all-cause death were: lower eGFR, lower BMI, male sex, sustained ventricular tachycardia or fibrillation (VT/VF), and the use of diuretics at discharge. Conclusions: Among patients hospitalized with HF, elderly patients had a worse prognosis than younger patients. Lower eGFR, lower BMI, male sex, sustained VT/VF, and diuretic use were independent predictors for all-cause death in these patients with higher risk. (Circ J 2011; 75: 2403-2410)
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN	1346-9843
EISSN	1347-4820
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1253/circj.CJ-11-0267