Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients With Heart Failure

Yamada, Shiro; Sakakibara, Mamoru; Yokota, Takashi et al.

Circulation Journal, 2013, 77(5), 1214-1220

Permalink : https://hdl.handle.net/2115/76973

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https://doi.org/10.1253/circj.CJ-12-1088     13

論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/76973
タイトル
Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients With Heart Failure
著者
Yamada, Shiro ; Sakakibara, Mamoru ; Yokota, Takashi ; Kamiya, Kiwamu ; Asakawa, Naoya ; Iwano, Hiroyuki ; Yamada, Satoshi ; Oba, Koji ; Tsutsui, Hiroyuki
著者名
Yamada, Shiro
e-Rad_Researcher
90349366
著者名
Sakakibara, Mamoru
e-Rad_Researcher
90374321
著者名
Yokota, Takashi
e-Rad_Researcher
60797108
著者名
Kamiya, Kiwamu
著者名
Asakawa, Naoya
e-Rad_Researcher
50622354
著者名
Iwano, Hiroyuki
e-Rad_Researcher
80374320
著者名
Yamada, Satoshi
著者名
Oba, Koji
e-Rad_Researcher
70264017
著者名
Tsutsui, Hiroyuki
言語
英語
キーワード
Adaptive servo-ventilation
Heart failure
Hemodynamics
Mitral regurgitation
Remodeling
発行日
2013
出版者
The Japanese Circulation Society
社団法人 日本循環器学会
収録物名
Circulation Journal
巻(号)
77(5)
ページ
1214-1220
抄録
Background: Adaptive servo-ventilation (ASV) improves cardiac function in patients with heart failure (HF). We compared the hemodynamics of control and HF patients, and identified the predictors for acute effects of ASV in HF. Methods and Results: We performed baseline echocardiographic measurements and hemodynamic measurements at baseline and after 15min of ASV during cardiac catheterization in 11 control and 34 HF patients. Heart rate and blood pressure did not change after ASV in either the control or HF group. Stroke volume index (SVI) decreased from 49.3±7.6 to 41.3±7.6ml/m2 in controls (P<0.0001) but did not change in the HF patients (from 34.8±11.5 to 32.8±8.9ml/m2, P=0.148). In the univariate analysis, pulmonary capillary wedge pressure (PCWP), mitral regurgitation (MR)/left atrial (LA) area, E/A, E/e’, and the sphericity index defined by the ratio between the short-axis and long-axis dimensions of the left ventricle significantly correlated with % change of SVI from baseline during ASV. PCWP and MR/LA area were independent predictors by multivariate analysis. Moreover, responders (15 of 34 HF patients; 44%) categorized by an increase in SVI showed significantly higher PCWP, MR, and sphericity index. Conclusions: Left ventricular structure and MR, as well as PCWP, could predict acute favorable effects on hemodynamics by ASV therapy in HF patients.  (Circ J 2013; 77: 1214–1220)
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN
1346-9843
EISSN
1347-4820
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.1253/circj.CJ-12-1088