A Simple Method for the Preparation of Stainless and Highly Pure Trichloroacetimidates

Ikeuchi, Kazutada; Murasawa, Kentaro; Yamada, Hidetoshi

Synlett, 2019, 30(11), 1308-1312

Permalink : https://hdl.handle.net/2115/78010

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ファイル	フォーマット	サイズ	閲覧回数	説明
Synlett 30(11) 1308	pdf	1.54 MB	1,186

アクセス権	open access
URI	https://hdl.handle.net/2115/78010
タイトル	A Simple Method for the Preparation of Stainless and Highly Pure Trichloroacetimidates
著者	Ikeuchi, Kazutada ; Murasawa, Kentaro ; Yamada, Hidetoshi
著者名 Ikeuchi, Kazutada
著者名 Murasawa, Kentaro
著者名 Yamada, Hidetoshi
言語	英語
キーワード	preparation
	2
	2
	2-trichloroacetimidates
	stainless
	solvent optimization
	visual detection
発行日	2019-07
出版者	Georg Thieme Verlag
収録物名	Synlett
巻(号)	30(11)
ページ	1308-1312
抄録	We describe a method for obtaining various allylic, benzylic, and glucosyl 2,2,2-trichloroacetimidates (TCAIs) as stainless liquids or solids at the crude stage. The general synthetic method for the preparation of TCAIs often leads to stained products, and further purification of crude TCAIs causes decomposition due to their instability. In the described method, we use a solvent that barely dissolves the reactant, providing stainless and sufficiently pure TCAIs without requiring a purification step. Furthermore, the reaction mixture is turbid at the beginning and clear at the end, allowing us to monitor the progress of the reaction visually.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0936-5214
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1055/s-0037-1611551