閲覧可能ファイル 

ファイル	フォーマット	サイズ	閲覧回数	説明
manuscript	pdf	555 KB	745

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/79109
タイトル	Catalytic Enantioselective Synthesis of Allylic Boronates Bearing a Trisubstituted Alkenyl Fluoride and Related Derivatives
著者	Akiyama, Sota ; Kubota, Koji ; Mikus, Malte S. ; Paioti, Paulo H. S. ; Romiti, Filippo ; Liu, Qinghe ; Zhou, Yuebiao ; Hoveyda, Amir H. ; Ito, Hajime
著者名 Akiyama, Sota
著者名 Kubota, Koji
著者名 Mikus, Malte S.
著者名 Paioti, Paulo H. S.
著者名 Romiti, Filippo
著者名 Liu, Qinghe
著者名 Zhou, Yuebiao
著者名 Hoveyda, Amir H.
e-Rad_Researcher 90282300 著者名 Ito, Hajime
言語	英語
キーワード	boron
	copper
	enantioselective catalysis
	fluorine
	synthetic methods
発行日	2020-06-13
出版者	Wiley-Blackwell
収録物名	Angewandte chemie-international edition
巻(号)	58(35)
ページ	11998-12003
抄録	The first catalytic method for diastereo- and enantioselective synthesis of allylic boronates bearing a Z-trisubstituted alkenyl fluoride is disclosed. Boryl substitution is performed with either a Z- or E-allyldifluoride and is catalyzed by bisphosphine/Cu complexes, affording products in up to 99 % yield with >98:2 Z/E selectivity and 99:1 enantiomeric ratio. A variety of subsequent modifications are feasible, and notable examples are diastereoselective additions to aldehydes/aldimines to access homoallylic alcohols/amines containing a fluorosubstituted stereogenic quaternary center.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is the peer reviewed version of the following article: S. Akiyama, K. Kubota, M. S. Mikus, P. H. S. Paioti, F. Romiti, Q. Liu, Y. Zhou, A. H. Hoveyda, H. Ito, Angew. Chem. Int. Ed. 2019, 58, 11998, which has been published in final form at https://doi.org/10.1002/anie.201906283. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
PISSN	1433-7851
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1002/anie.201906283

ホームへ戻る