Isolation of Candidatus Bartonella rousetti and Other Bat-associated Bartonellae from Bats and Their Flies in Zambia

Qiu, Yongjin; Kajihara, Masahiro; Nakao, Ryo; Mulenga, Evans; Harima, Hayato; Hang'ombe, Bernard Mudenda; Eto, Yoshiki; Changula, Katendi; Mwizabi, Daniel; Sawa, Hirofumi; Higashi, Hideaki; Mweene, Aaron; Takada, Ayato; Simuunza, Martin; Sugimoto, Chihiro

Isolation of Candidatus Bartonella rousetti and Other Bat-associated Bartonellae from Bats and Their Flies in Zambia

Qiu, Yongjin; Kajihara, Masahiro; Nakao, Ryo et al.

Pathogens, 2020, 9(6), 469

Permalink : https://hdl.handle.net/2115/79174

このアイテムのアクセス数:601件（2026-08-11 10:41 集計）

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https://doi.org/10.3390/pathogens9060469			30

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アクセス権	open access
URI	https://hdl.handle.net/2115/79174
タイトル	Isolation of Candidatus Bartonella rousetti and Other Bat-associated Bartonellae from Bats and Their Flies in Zambia
著者	Qiu, Yongjin ; Kajihara, Masahiro ; Nakao, Ryo ; Mulenga, Evans ; Harima, Hayato ; Hang'ombe, Bernard Mudenda ; Eto, Yoshiki ; Changula, Katendi ; Mwizabi, Daniel ; Sawa, Hirofumi ; Higashi, Hideaki ; Mweene, Aaron ; Takada, Ayato ; Simuunza, Martin ; Sugimoto, Chihiro
著者名 Qiu, Yongjin
著者名 Kajihara, Masahiro
著者名 Nakao, Ryo
著者名 Mulenga, Evans
著者名 Harima, Hayato
著者名 Hang'ombe, Bernard Mudenda
著者名 Eto, Yoshiki
著者名 Changula, Katendi
著者名 Mwizabi, Daniel
著者名 Sawa, Hirofumi
著者名 Higashi, Hideaki
著者名 Mweene, Aaron
著者名 Takada, Ayato
著者名 Simuunza, Martin
e-Rad_Researcher 90231373 著者名 Sugimoto, Chihiro
言語	英語
キーワード	Bartonella
	bat fly
	bat
	PCR
	isolation
	Zambia
発行日	2020-06
出版者	MDPI
収録物名	Pathogens
巻(号)	9(6)
ページ	469
抄録	Bat-associated bartonellae, including Bartonella mayotimonensis and Candidatus Bartonella rousetti, were recently identified as emerging and potential zoonotic agents, respectively. However, there is no report of bat-associated bartonellae in Zambia. Thus, we aimed to isolate and characterize Bartonella spp. from bats and bat flies captured in Zambia by culturing and PCR. Overall, Bartonella spp. were isolated from six out of 36 bats (16.7%), while Bartonella DNA was detected in nine out of 19 bat flies (47.3%). Subsequent characterization using a sequence of five different genes revealed that three isolates obtained from Egyptian fruit bats (Rousettus aegyptiacus) were Ca. B. rousetti. The isolates obtained from insectivorous bats (Macronycteris vittatus) were divided into two previously unclassified bat-associated bartonellae. A phylogenetic analysis of the six genotypes of Bartonella gltA sequences from nine pathogen-positive bat flies revealed that three genotypes belonged to the same clades as bat-associated bartonellae, including Ca. B. rousetti. The other three genotypes represented arthropod-associated bartonellae, which have previously been isolated only from ectoparasites. We demonstrated that Ca. B. rousetti is maintained between bats (R. aegyptiacus) and bat flies in Zambia. Continuous surveillance of Bartonella spp. in bats and serological surveys in humans in Africa are warranted to evaluate the public health importance of bat-associated bartonellae.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3390/pathogens9060469