Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis

Komori, Akira; Abe, Toshikazu; Kushimoto, Shigeki; Ogura, Hiroshi; Shiraishi, Atsushi; Saitoh, Daizoh; Fujishima, Seitaro; Mayumi, Toshihiko; Naito, Toshio; Hifumi, Toru; Shiino, Yasukazu; Nakada, Taka-aki; Tarui, Takehiko; Otomo, Yasuhiro; Okamoto, Kohji; Umemura, Yutaka; Kotani, Joji; Sakamoto, Yuichiro; Sasaki, Junichi; Shiraishi, Shin-ichiro; Takuma, Kiyotsugu; Tsuruta, Ryosuke; Hagiwara, Akiyoshi; Yamakawa, Kazuma; Masuno, Tomohiko; Takeyama, Naoshi; Yamashita, Norio; Ikeda, Hiroto; Ueyama, Masashi; Fujimi, Satoshi; Gando, Satoshi

Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis

Komori, Akira; Abe, Toshikazu; Kushimoto, Shigeki et al.

Scientific reports, 2020, 10(1), 2983

Permalink : https://hdl.handle.net/2115/79484

このアイテムのアクセス数:563件（2026-08-18 06:25 集計）

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https://doi.org/10.1038/s41598-020-59830-6			10

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アクセス権	open access
URI	https://hdl.handle.net/2115/79484
タイトル	Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis
著者	Komori, Akira ; Abe, Toshikazu ; Kushimoto, Shigeki ; Ogura, Hiroshi ; Shiraishi, Atsushi ; Saitoh, Daizoh ; Fujishima, Seitaro ; Mayumi, Toshihiko ; Naito, Toshio ; Hifumi, Toru ; Shiino, Yasukazu ; Nakada, Taka-aki ; Tarui, Takehiko ; Otomo, Yasuhiro ; Okamoto, Kohji ; Umemura, Yutaka ; Kotani, Joji ; Sakamoto, Yuichiro ; Sasaki, Junichi ; Shiraishi, Shin-ichiro ; Takuma, Kiyotsugu ; Tsuruta, Ryosuke ; Hagiwara, Akiyoshi ; Yamakawa, Kazuma ; Masuno, Tomohiko ; Takeyama, Naoshi ; Yamashita, Norio ; Ikeda, Hiroto ; Ueyama, Masashi ; Fujimi, Satoshi ; Gando, Satoshi
著者名 Komori, Akira
e-Rad_Researcher 70633973 著者名 Abe, Toshikazu
e-Rad_Researcher 50195434 著者名 Kushimoto, Shigeki
e-Rad_Researcher 70301265 著者名 Ogura, Hiroshi
e-Rad_Researcher 40401343 著者名 Shiraishi, Atsushi
e-Rad_Researcher 90531632 著者名 Saitoh, Daizoh
e-Rad_Researcher 00173419 著者名 Fujishima, Seitaro
e-Rad_Researcher 90281071 著者名 Mayumi, Toshihiko
著者名 Naito, Toshio
著者名 Hifumi, Toru
著者名 Shiino, Yasukazu
e-Rad_Researcher 20375794 著者名 Nakada, Taka-aki
著者名 Tarui, Takehiko
e-Rad_Researcher 40176946 著者名 Otomo, Yasuhiro
著者名 Okamoto, Kohji
e-Rad_Researcher 20743561 著者名 Umemura, Yutaka
e-Rad_Researcher 80360270 著者名 Kotani, Joji
e-Rad_Researcher 20366678 著者名 Sakamoto, Yuichiro
e-Rad_Researcher 90235250 著者名 Sasaki, Junichi
e-Rad_Researcher 90386243 著者名 Shiraishi, Shin-ichiro
e-Rad_Researcher 30216824 著者名 Takuma, Kiyotsugu
e-Rad_Researcher 30263768 著者名 Tsuruta, Ryosuke
著者名 Hagiwara, Akiyoshi
e-Rad_Researcher 50597507 著者名 Yamakawa, Kazuma
e-Rad_Researcher 00318528 著者名 Masuno, Tomohiko
e-Rad_Researcher 00155053 著者名 Takeyama, Naoshi
著者名 Yamashita, Norio
著者名 Ikeda, Hiroto
著者名 Ueyama, Masashi
著者名 Fujimi, Satoshi
e-Rad_Researcher 30125306 著者名 Gando, Satoshi
言語	英語
発行日	2020-02-19
出版者	Nature Publishing Group
収録物名	Scientific reports
巻(号)	10(1)
ページ	2983
抄録	The clinical implications of bacteremia among septic patients remain unclear, although a vast amount of data have been accumulated on sepsis. We aimed to compare the clinical characteristics and outcomes of severe sepsis patients with and without bacteremia. This secondary analysis of a multicenter, prospective cohort study included 59 intensive care units (ICUs) in Japan between January 2016 and March 2017. The study cohort comprised 1,184 adults (aged >= 16 years) who were admitted to an ICU with severe sepsis and diagnosed according to the Sepsis-2 criteria. Of 1,167 patients included in the analysis, 636 (54.5%) had bacteremia. Those with bacteremia had significantly higher rates of septic shock (66.4% vs. 58.9%, p=0.01) and higher sepsis severity scores, including the Acute Physiology and Chronic Health Evaluation (APACHE) II and the Sequential Organ Failure Assessment (SOFA). No significant difference in in-hospital mortality was seen between patients with and without bacteremia (25.6% vs. 21.0%, p=0.08). In conclusion, half of severe sepsis patients in ICUs have bacteremia. Although patients with bacteremia had more severe state, between-group differences in patient-centered outcomes, such as in-hospital mortality, have not been fully elucidated.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	2045-2322
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1038/s41598-020-59830-6