Laparoscopic-assisted distal gastrectomy and central pancreatectomy for gastric and perigastric lymph node metastases and pancreatic invasion from melanoma : a case report

Okawa, Yuki; Ebihara, Yuma; Tanaka, Kimitaka; Nakanishi, Yoshitsugu; Asano, Toshimichi; Noji, Takehiro; Kurashima, Yo; Murakami, Soichi; Nakamura, Toru; Tsuchikawa, Takahiro; Okamura, Keisuke; Shichinohe, Toshiaki; Hirano, Satoshi

Laparoscopic-assisted distal gastrectomy and central pancreatectomy for gastric and perigastric lymph node metastases and pancreatic invasion from melanoma : a case report

Okawa, Yuki; Ebihara, Yuma; Tanaka, Kimitaka et al.

Surgical case reports, 2020, 6(1), 239

Permalink : https://hdl.handle.net/2115/79759

このアイテムのアクセス数:585件（2026-10-14 03:29 集計）

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アクセス権	open access
URI	https://hdl.handle.net/2115/79759
タイトル	Laparoscopic-assisted distal gastrectomy and central pancreatectomy for gastric and perigastric lymph node metastases and pancreatic invasion from melanoma : a case report
著者	Okawa, Yuki ; Ebihara, Yuma ; Tanaka, Kimitaka ; Nakanishi, Yoshitsugu ; Asano, Toshimichi ; Noji, Takehiro ; Kurashima, Yo ; Murakami, Soichi ; Nakamura, Toru ; Tsuchikawa, Takahiro ; Okamura, Keisuke ; Shichinohe, Toshiaki ; Hirano, Satoshi
著者名 Okawa, Yuki
e-Rad_Researcher 50632981 著者名 Ebihara, Yuma
e-Rad_Researcher 10758642 著者名 Tanaka, Kimitaka
e-Rad_Researcher 40447058 著者名 Nakanishi, Yoshitsugu
e-Rad_Researcher 10756688 著者名 Asano, Toshimichi
e-Rad_Researcher 10739296 著者名 Noji, Takehiro
e-Rad_Researcher 40374350 著者名 Kurashima, Yo
e-Rad_Researcher 80706573 著者名 Murakami, Soichi
e-Rad_Researcher 70645796 著者名 Nakamura, Toru
e-Rad_Researcher 50507572 著者名 Tsuchikawa, Takahiro
e-Rad_Researcher 90724401 著者名 Okamura, Keisuke
e-Rad_Researcher 70374353 著者名 Shichinohe, Toshiaki
e-Rad_Researcher 50322813 著者名 Hirano, Satoshi
言語	英語
キーワード	Malignant melanoma
	Central pancreatectomy
	Laparoscopic distal gastrectomy
発行日	2020-09-29
出版者	Springer
収録物名	Surgical case reports
巻(号)	6(1)
ページ	239
抄録	Background In melanoma, completely resectable metastases are surgically resected to expect to prolong relapse-free survival and overall survival. However, distant metastases of melanoma are rarely indicated for surgery because multiple metastases are often observed at diagnosis. We report a case of a man in his 50s who underwent laparoscopic-assisted distal gastrectomy and central pancreatectomy for gastric metastases, lymph node metastases, and pancreatic invasion that could be completely resected. Case presentation A 50-year-old man was diagnosed with malignant melanoma of the left parietal region. After diagnosis, tumor resection and left cervical lymph node dissection were performed, and interferon-beta treatment was added as adjuvant therapy. Seventeen months after adjuvant therapy, metastasis of stomach and abdominal lymph nodes from melanoma was diagnosed. And the pancreatic invasion of lymph nodes was suspected. Laparoscopic-assisted distal gastrectomy and the central pancreatectomy were performed because pancreatic invasion of melanoma was intraoperatively found. After 9 months of relapse-free survival, abdominal recurrence was observed. Nivolumab and ipilimumab were administered, and recurrent lesions are currently controlled. The patient has survived more than 3 years since metastasis resection. Conclusion In conclusion, laparoscopic-assisted distal gastrectomy and the central pancreatectomy were performed for gastric and perigastric lymph node metastases and pancreatic invasion due to malignant melanoma, and the negative surgical margin was achieved. Although patient selection is required, the central pancreatectomy was a good indication for maintaining exocrine and endocrine function. The development of immune checkpoint inhibitors and molecular-targeted agents may increase gastrointestinal surgery for metastatic melanoma in the future.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	2198-7793
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1186/s40792-020-01027-0