A new SOBP-formation method by superposing specially shaped Bragg curves formed by a mini-ridge filter for spot scanning in proton beam therapy

Yokokawa, Kohei; Furusaka, M.; Matsuura, T.; Hirayama, S.; Umegaki, Kikuo

A new SOBP-formation method by superposing specially shaped Bragg curves formed by a mini-ridge filter for spot scanning in proton beam therapy

Yokokawa, Kohei; Furusaka, M.; Matsuura, T. et al.

Physica medica : European journal of medical physics, 2019, 67, 70-76

Permalink : https://hdl.handle.net/2115/79824

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アクセス権	open access
URI	https://hdl.handle.net/2115/79824
タイトル	A new SOBP-formation method by superposing specially shaped Bragg curves formed by a mini-ridge filter for spot scanning in proton beam therapy
著者	Yokokawa, Kohei ; Furusaka, M. ; Matsuura, T. ; Hirayama, S. ; Umegaki, Kikuo
著者名 Yokokawa, Kohei
著者名 Furusaka, M.
著者名 Matsuura, T.
著者名 Hirayama, S.
e-Rad_Researcher 40643193 著者名 Umegaki, Kikuo
言語	英語
キーワード	Spot-scanning proton therapy
	Low-energy proton beam
	Spread-out Bragg peak
	Mini-ridge filter
発行日	2019-11
出版者	Elsevier
収録物名	Physica medica : European journal of medical physics
巻(号)	67
ページ	70-76
抄録	Purpose: We propose a new spread-out Bragg peak (SOBP) formation method for low-energy regions of spot-scanning proton therapy in order to reduce the required number of energy layers while maintaining high dose uniformity, while maintaining the distal falloff as sharp as possible. Methods: We use only one specially shaped mini-ridge filter (MRF) to create new trapezoidal Bragg curves (TBCs) from very sharp pristine Bragg curves (PBCs) of low-energy proton beams. The TBC has three pre-designed dose regions of proximal, flat-top, and distal components. These components are designed to have nearly equal depth lengths and good linearity. Then, the required SOBP is formed by superposing the TBCs with the correct spacing and beam intensity weights. We then compare the performance of the TBC-based SOBPs with those formed by PBCs. Results: The dose uniformities of the SOBP formed by the proposed method are kept within the design tolerance, and are equivalent to those of conventional SOBPs. The sharpness of the distal falloff is reasonably kept by the deepest TBC. The required number of energy layers is significantly reduced compared with that of conventional PBC-based SOBP. Conclusions: The proposed method enables shortening of the irradiation time of spot-scanning proton beam therapy in low-energy regions with a reduced number of energy layers. It can be realized by using only one specially shaped MRF, which can be easily installed at any facility.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2019, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	1120-1797
EISSN	1724-191X
NCID	AA12796015
関連情報	PMID 31678799
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.ejmp.2019.10.036