A New Variant among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019

Twabela, Augustin T.; Lam, Thanh Nguyen; Masumu, Justin; Mpoyo, Patrick; Mpiana, Serge; Sumbu, Julienne; Okamatsu, Masatoshi; Matsuno, Keita; Isoda, Norikazu; Zecchin, Bianca; Monne, Isabella; Sakoda, Yoshihiro

A New Variant among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019

Twabela, Augustin T.; Lam, Thanh Nguyen; Masumu, Justin et al.

Viruses-Basel, 2021, 13(2), 151

Permalink : https://hdl.handle.net/2115/81219

このアイテムのアクセス数:487件（2026-08-17 08:29 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
https://doi.org/10.3390/v13020151			35

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/81219
タイトル	A New Variant among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019
著者	Twabela, Augustin T. ; Lam, Thanh Nguyen ; Masumu, Justin ; Mpoyo, Patrick ; Mpiana, Serge ; Sumbu, Julienne ; Okamatsu, Masatoshi ; Matsuno, Keita ; Isoda, Norikazu ; Zecchin, Bianca ; Monne, Isabella ; Sakoda, Yoshihiro
著者名 Twabela, Augustin T.
著者名 Lam, Thanh Nguyen
著者名 Masumu, Justin
著者名 Mpoyo, Patrick
著者名 Mpiana, Serge
著者名 Sumbu, Julienne
e-Rad_Researcher 00507163 著者名 Okamatsu, Masatoshi
e-Rad_Researcher 40753306 著者名 Matsuno, Keita
e-Rad_Researcher 80615732 著者名 Isoda, Norikazu
著者名 Zecchin, Bianca
著者名 Monne, Isabella
e-Rad_Researcher 40333637 著者名 Sakoda, Yoshihiro
言語	英語
キーワード	new variant
	Newcastle disease virus
	chicken outbreak
	Democratic Republic of the Congo
発行日	2021-02
出版者	MDPI
収録物名	Viruses-Basel
巻(号)	13(2)
ページ	151
抄録	Newcastle disease (ND) is a highly transmissible and devastating disease that affects poultry and wild birds worldwide. Comprehensive knowledge regarding the characteristics and epidemiological factors of the ND virus (NDV) is critical for the control and prevention of ND. Effective vaccinations can prevent and control the spread of the NDV in poultry populations. For decades, the Democratic Republic of the Congo (DRC) has reported the impacts of ND on commercial and traditional poultry farming systems. The reports were preliminary clinical observations, and few cases were confirmed in the laboratory. However, data on the phylogenetic, genetic, and virological characteristics of NDVs circulating in the DRC are not available. In this study, the whole-genome sequences of three NDV isolates obtained using the next-generation sequencing method revealed two isolates that were a new variant of NDV, and one isolate that was clustered in the subgenotype VII.2. All DRC isolates were velogenic and were antigenically closely related to the vaccine strains. Our findings reveal that despite the circulation of the new variant, ND can be controlled in the DRC using the current vaccine. However, epidemiological studies should be conducted to elucidate the endemicity of the disease so that better control strategies can be implemented.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution 4.0 International
PISSN	1999-4915
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3390/v13020151